Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum

Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum

week after immunization (specific activity is identified using neutralization reaction on the model of white mice and dot-blot immunoassay). This level of activity is sufficient for the fractioning of immune serum and extraction of anti-rabies immunoglobulin. Physicochemical and biological propertie...

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Main Authors: S. V. Generalov, E. G. Abramova, Zh. V. Matveeva, I. M. Zhulidov, O. A. Lobovikova, R. A. Svintsov, A. V. Komissarov, M. N. Kireev, A. K. Nikiforov
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2012-08-01
Series:Проблемы особо опасных инфекций
Subjects:
антирабический иммуноглобулин
вирус бешенства
культуральный антиген
anti-rabies immunoglobulin
rabies virus
cultural antigen
Online Access:https://journal.microbe.ru/jour/article/view/876
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spelling doaj-68df55cecc3e42b28347fc5a3e9ade7d2021-07-22T07:51:35ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2012-08-0104(114)656810.21055/0370-1069-2012-4-65-68860Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood SerumS. V. Generalov0E. G. Abramova1Zh. V. Matveeva2I. M. Zhulidov3O. A. Lobovikova4R. A. Svintsov5A. V. Komissarov6M. N. Kireev7A. K. Nikiforov8Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”Russian Research Anti-Plague Institute “Microbe”week after immunization (specific activity is identified using neutralization reaction on the model of white mice and dot-blot immunoassay). This level of activity is sufficient for the fractioning of immune serum and extraction of anti-rabies immunoglobulin. Physicochemical and biological properties of the anti-rabies immunoglobulin, obtained with the help of cultural antigen technique, meet the requirements stated in the normative documentation on anti-rabies immunoglobulins extracted from equine blood serum. Specific activity level of experimental batches of anti-rabies immunoglobulin, obtained with the help of cultural technologies, corresponds to 242 and 214 IU/ml.https://journal.microbe.ru/jour/article/view/876антирабический иммуноглобулинвирус бешенствакультуральный антигенanti-rabies immunoglobulinrabies viruscultural antigen
collection DOAJ
language Russian
format Article
sources DOAJ
author S. V. Generalov
E. G. Abramova
Zh. V. Matveeva
I. M. Zhulidov
O. A. Lobovikova
R. A. Svintsov
A. V. Komissarov
M. N. Kireev
A. K. Nikiforov
spellingShingle S. V. Generalov
E. G. Abramova
Zh. V. Matveeva
I. M. Zhulidov
O. A. Lobovikova
R. A. Svintsov
A. V. Komissarov
M. N. Kireev
A. K. Nikiforov
Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum
Проблемы особо опасных инфекций
антирабический иммуноглобулин
вирус бешенства
культуральный антиген
anti-rabies immunoglobulin
rabies virus
cultural antigen
author_facet S. V. Generalov
E. G. Abramova
Zh. V. Matveeva
I. M. Zhulidov
O. A. Lobovikova
R. A. Svintsov
A. V. Komissarov
M. N. Kireev
A. K. Nikiforov
author_sort S. V. Generalov
title Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum
title_short Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum
title_full Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum
title_fullStr Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum
title_full_unstemmed Cultural Antigen in the Technology for Anti-Rabies Immunoglobulin Obtainment from Equine Blood Serum
title_sort cultural antigen in the technology for anti-rabies immunoglobulin obtainment from equine blood serum
publisher Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
series Проблемы особо опасных инфекций
issn 0370-1069
2658-719X
publishDate 2012-08-01
description week after immunization (specific activity is identified using neutralization reaction on the model of white mice and dot-blot immunoassay). This level of activity is sufficient for the fractioning of immune serum and extraction of anti-rabies immunoglobulin. Physicochemical and biological properties of the anti-rabies immunoglobulin, obtained with the help of cultural antigen technique, meet the requirements stated in the normative documentation on anti-rabies immunoglobulins extracted from equine blood serum. Specific activity level of experimental batches of anti-rabies immunoglobulin, obtained with the help of cultural technologies, corresponds to 242 and 214 IU/ml.
topic антирабический иммуноглобулин
вирус бешенства
культуральный антиген
anti-rabies immunoglobulin
rabies virus
cultural antigen
url https://journal.microbe.ru/jour/article/view/876
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AT imzhulidov culturalantigeninthetechnologyforantirabiesimmunoglobulinobtainmentfromequinebloodserum
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AT rasvintsov culturalantigeninthetechnologyforantirabiesimmunoglobulinobtainmentfromequinebloodserum
AT avkomissarov culturalantigeninthetechnologyforantirabiesimmunoglobulinobtainmentfromequinebloodserum
AT mnkireev culturalantigeninthetechnologyforantirabiesimmunoglobulinobtainmentfromequinebloodserum
AT aknikiforov culturalantigeninthetechnologyforantirabiesimmunoglobulinobtainmentfromequinebloodserum
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