The untold story between enhancers and skeletal muscle development

Currently, enhancers have key transcriptional regulatory roles in muscle development. Skeletal muscle formation involves various molecules, and in animals, enhancers are one of the main types of transcriptional regulatory regions that are of great importance to regulate myogenic gene expression. In...

Full description

Bibliographic Details
Main Authors:	Yong-sheng ZHANG, Dan LU, Yu-wen LIU, Guo-qiang YI, Zhong-lin TANG
Format:	Article
Language:	English
Published:	Elsevier 2020-09-01
Series:	Journal of Integrative Agriculture
Subjects:	animal enhancer eRNA skeletal muscle growth and development
Online Access:	http://www.sciencedirect.com/science/article/pii/S209531192063235X

id	doaj-68e49b4168ed44f8b81e75927d5269cc
record_format	Article
spelling	doaj-68e49b4168ed44f8b81e75927d5269cc2021-06-08T04:42:40ZengElsevierJournal of Integrative Agriculture2095-31192020-09-0119921372149The untold story between enhancers and skeletal muscle developmentYong-sheng ZHANG0Dan LU1Yu-wen LIU2Guo-qiang YI3Zhong-lin TANG4Shenzhen Branch Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.China; Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.China; Correspondence ZHANG Yong-sheng, Tel: +86-755-23251432College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, P.R.ChinaShenzhen Branch Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.China; Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.ChinaShenzhen Branch Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.China; Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.ChinaShenzhen Branch Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.China; Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, P.R.China; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.China; Correspondence TANG Zhong-linCurrently, enhancers have key transcriptional regulatory roles in muscle development. Skeletal muscle formation involves various molecules, and in animals, enhancers are one of the main types of transcriptional regulatory regions that are of great importance to regulate myogenic gene expression. In muscle development, enhancers can generate enhancer RNAs (eRNAs) that are involved in the regulation of gene transcription. The regulation of gene expression by eRNAs offers great potential in improving animal production traits. Herein we comprehensively review the roles of enhancers in muscle formation and its potential function in skeletal muscle development. This review will describe the future application of enhancers in skeletal muscle development and discuss the prospects that enhancer studies offer for agriculture, biotechnology, and animal breeding.http://www.sciencedirect.com/science/article/pii/S209531192063235XanimalenhancereRNAskeletal musclegrowth and development
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yong-sheng ZHANG Dan LU Yu-wen LIU Guo-qiang YI Zhong-lin TANG
spellingShingle	Yong-sheng ZHANG Dan LU Yu-wen LIU Guo-qiang YI Zhong-lin TANG The untold story between enhancers and skeletal muscle development Journal of Integrative Agriculture animal enhancer eRNA skeletal muscle growth and development
author_facet	Yong-sheng ZHANG Dan LU Yu-wen LIU Guo-qiang YI Zhong-lin TANG
author_sort	Yong-sheng ZHANG
title	The untold story between enhancers and skeletal muscle development
title_short	The untold story between enhancers and skeletal muscle development
title_full	The untold story between enhancers and skeletal muscle development
title_fullStr	The untold story between enhancers and skeletal muscle development
title_full_unstemmed	The untold story between enhancers and skeletal muscle development
title_sort	untold story between enhancers and skeletal muscle development
publisher	Elsevier
series	Journal of Integrative Agriculture
issn	2095-3119
publishDate	2020-09-01
description	Currently, enhancers have key transcriptional regulatory roles in muscle development. Skeletal muscle formation involves various molecules, and in animals, enhancers are one of the main types of transcriptional regulatory regions that are of great importance to regulate myogenic gene expression. In muscle development, enhancers can generate enhancer RNAs (eRNAs) that are involved in the regulation of gene transcription. The regulation of gene expression by eRNAs offers great potential in improving animal production traits. Herein we comprehensively review the roles of enhancers in muscle formation and its potential function in skeletal muscle development. This review will describe the future application of enhancers in skeletal muscle development and discuss the prospects that enhancer studies offer for agriculture, biotechnology, and animal breeding.
topic	animal enhancer eRNA skeletal muscle growth and development
url	http://www.sciencedirect.com/science/article/pii/S209531192063235X
work_keys_str_mv	AT yongshengzhang theuntoldstorybetweenenhancersandskeletalmuscledevelopment AT danlu theuntoldstorybetweenenhancersandskeletalmuscledevelopment AT yuwenliu theuntoldstorybetweenenhancersandskeletalmuscledevelopment AT guoqiangyi theuntoldstorybetweenenhancersandskeletalmuscledevelopment AT zhonglintang theuntoldstorybetweenenhancersandskeletalmuscledevelopment AT yongshengzhang untoldstorybetweenenhancersandskeletalmuscledevelopment AT danlu untoldstorybetweenenhancersandskeletalmuscledevelopment AT yuwenliu untoldstorybetweenenhancersandskeletalmuscledevelopment AT guoqiangyi untoldstorybetweenenhancersandskeletalmuscledevelopment AT zhonglintang untoldstorybetweenenhancersandskeletalmuscledevelopment
_version_	1721390267032928256

The untold story between enhancers and skeletal muscle development

Similar Items