Trichodermin (4β-acetoxy-12,13-epoxytrichothec-9-ene)

In the title natural product, C17H24O4, which is a very potent inhibitor of protein synthesis in mammalian cells, the five-membered ring displays an envelope conformation, whereas the two six-membered rings show different conformations, viz. chair and half-chair.

Bibliographic Details
Main Authors: Fu-Cheng Lin, Yu-Zhe Chen, Chu-Long Zhang, Shao-Yuan Chen
Format: Article
Language:English
Published: International Union of Crystallography 2008-04-01
Series:Acta Crystallographica Section E
Online Access:http://scripts.iucr.org/cgi-bin/paper?S1600536808006168