Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses
It is shown that in patients with acute hepatitis B with concomitant chronic alcohol consumption in hepatotoxic doses in acute period of the disease is characterized by low serum levels of interleukin-2 and high levels of interleukin-8, compared with patients without this cofactor. In the convalesce...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Publishing House Zaslavsky
2014-02-01
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| Series: | Aktualʹnaâ Infektologiâ |
| Subjects: | |
| Online Access: | http://ai.zaslavsky.com.ua/article/view/82288 |
| Summary: | It is shown that in patients with acute hepatitis B with concomitant chronic alcohol consumption in hepatotoxic doses in acute period of the disease is characterized by low serum levels of interleukin-2 and high levels of interleukin-8, compared with patients without this cofactor. In the convalescence period in these patients there remains an imbalance in cytokine status due to low serum levels of interleukin-2 and a high level of interleukin-6 and interleukin-8 that is accompanied by high activity of alanine-aminotransferase, more frequent HBsAg blood circulating and less seroconversion rate with anti-Hbe presence. |
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| ISSN: | 2312-413X 2312-4148 |