Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses
It is shown that in patients with acute hepatitis B with concomitant chronic alcohol consumption in hepatotoxic doses in acute period of the disease is characterized by low serum levels of interleukin-2 and high levels of interleukin-8, compared with patients without this cofactor. In the convalesce...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Publishing House Zaslavsky
2014-02-01
|
Series: | Aktualʹnaâ Infektologiâ |
Subjects: | |
Online Access: | http://ai.zaslavsky.com.ua/article/view/82288 |
id |
doaj-6912fc42fa1a4a1da7e3d5121bdfb67f |
---|---|
record_format |
Article |
spelling |
doaj-6912fc42fa1a4a1da7e3d5121bdfb67f2020-11-24T22:31:17ZengPublishing House ZaslavskyAktualʹnaâ Infektologiâ2312-413X2312-41482014-02-0121.02485110.22141/2312-413x.1.02.2014.8228882288Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic DosesO.V. Rуabokon’0O.O. Furyk1Zaporozhye State Medical University, Zaporozhye, UkraineZaporozhye State Medical University, Zaporozhye, UkraineIt is shown that in patients with acute hepatitis B with concomitant chronic alcohol consumption in hepatotoxic doses in acute period of the disease is characterized by low serum levels of interleukin-2 and high levels of interleukin-8, compared with patients without this cofactor. In the convalescence period in these patients there remains an imbalance in cytokine status due to low serum levels of interleukin-2 and a high level of interleukin-6 and interleukin-8 that is accompanied by high activity of alanine-aminotransferase, more frequent HBsAg blood circulating and less seroconversion rate with anti-Hbe presence.http://ai.zaslavsky.com.ua/article/view/82288acute hepatitis Bcytokineschronic alcohol consupmtion in hepatotoxic doses |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
O.V. Rуabokon’ O.O. Furyk |
spellingShingle |
O.V. Rуabokon’ O.O. Furyk Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses Aktualʹnaâ Infektologiâ acute hepatitis B cytokines chronic alcohol consupmtion in hepatotoxic doses |
author_facet |
O.V. Rуabokon’ O.O. Furyk |
author_sort |
O.V. Rуabokon’ |
title |
Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses |
title_short |
Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses |
title_full |
Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses |
title_fullStr |
Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses |
title_full_unstemmed |
Dynamics of Clinical-Biochemical and Immunological Parameters in Patients with Acute Hepatitis B Accompanied by Chronic Alcohol Consumption in Hepatotoxic Doses |
title_sort |
dynamics of clinical-biochemical and immunological parameters in patients with acute hepatitis b accompanied by chronic alcohol consumption in hepatotoxic doses |
publisher |
Publishing House Zaslavsky |
series |
Aktualʹnaâ Infektologiâ |
issn |
2312-413X 2312-4148 |
publishDate |
2014-02-01 |
description |
It is shown that in patients with acute hepatitis B with concomitant chronic alcohol consumption in hepatotoxic doses in acute period of the disease is characterized by low serum levels of interleukin-2 and high levels of interleukin-8, compared with patients without this cofactor. In the convalescence period in these patients there remains an imbalance in cytokine status due to low serum levels of interleukin-2 and a high level of interleukin-6 and interleukin-8 that is accompanied by high activity of alanine-aminotransferase, more frequent HBsAg blood circulating and less seroconversion rate with anti-Hbe presence. |
topic |
acute hepatitis B cytokines chronic alcohol consupmtion in hepatotoxic doses |
url |
http://ai.zaslavsky.com.ua/article/view/82288 |
work_keys_str_mv |
AT ovruabokon dynamicsofclinicalbiochemicalandimmunologicalparametersinpatientswithacutehepatitisbaccompaniedbychronicalcoholconsumptioninhepatotoxicdoses AT oofuryk dynamicsofclinicalbiochemicalandimmunologicalparametersinpatientswithacutehepatitisbaccompaniedbychronicalcoholconsumptioninhepatotoxicdoses |
_version_ |
1725737827261480960 |