Transcriptional landscape of PTEN loss in primary prostate cancer

Transcriptional landscape of PTEN loss in primary prostate cancer

Abstract Background PTEN is the most frequently lost tumor suppressor in primary prostate cancer (PCa) and its loss is associated with aggressive disease. However, the transcriptional changes associated with PTEN loss in PCa have not been described in detail. In this study, we highlight the transcri...

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Bibliographic Details
Main Authors: Eddie Luidy Imada, Diego Fernando Sanchez, Wikum Dinalankara, Thiago Vidotto, Ericka M. Ebot, Svitlana Tyekucheva, Gloria Regina Franco, Lorelei Ann Mucci, Massimo Loda, Edward Matthew Schaeffer, Tamara Lotan, Luigi Marchionni
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Cancer
Subjects:
Prostate Cancer
PTEN deletion
PTEN loss
Non-coding RNA
lncRNA
Meta-analysis
Online Access:https://doi.org/10.1186/s12885-021-08593-y

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