Loss of progesterone receptor-mediated actions induce preterm cellular and structural remodeling of the cervix and premature birth.

Loss of progesterone receptor-mediated actions induce preterm cellular and structural remodeling of the cervix and premature birth.

A decline in serum progesterone or antagonism of progesterone receptor function results in preterm labor and birth. Whether characteristics of premature remodeling of the cervix after antiprogestins or ovariectomy are similar to that at term was the focus of the present study. Groups of pregnant rat...

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Bibliographic Details
Main Authors: Steven M Yellon, Abigail E Dobyns, Hailey L Beck, James T Kurtzman, Robert E Garfield, Michael A Kirby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3858221?pdf=render

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