Factors associated with multidrug-resistant tuberculosis
This case control study was conducted in selected centers of Dhaka City from March to July 2008 to determine the association of multidrug-resistant tuberculosis with the attributes related to treatment and socio-economic condition of tuberculosis patients. Sixty seven culture-proven multidrug-resist...
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Ibrahim Medical College
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doaj-6947eef4bad94b24b9b3478be5e1a19c2020-11-25T00:18:21ZengIbrahim Medical CollegeIMC Journal of Medical Science2519-17212519-15862009-01-01312933Factors associated with multidrug-resistant tuberculosisMd Nurul Amin0Md Anisur Rahman1Meerjady Sabrina Flora2Md Abul Kalam Azad3GSO-II, R & P, Armed Forces Medical Institute, Dhaka Cantonment, DhakaDepartment of Epidemiology, National Institute of Preventive & Social Medicine (NIPSOM), Mohakhali, DhakaDepartment of Epidemiology, National Institute of Preventive & Social Medicine (NIPSOM), Mohakhali, DhakaGSO-II, R & P, Armed Forces Medical Institute, Dhaka Cantonment, DhakaThis case control study was conducted in selected centers of Dhaka City from March to July 2008 to determine the association of multidrug-resistant tuberculosis with the attributes related to treatment and socio-economic condition of tuberculosis patients. Sixty seven culture-proven multidrug-resistant tuberculosis cases and similar number of age and sex matched controls were selected purposively. Data were collected by face to face interview and documents’ review, using a pre tested structured questionnaire and a checklist. Multidrug-resistance was found to be associated with occupation (p=0.001) and residential status (p=0.001) of the tuberculosis patients. Tuberculosis patients who did not remain under directly observed treatment were 3 times more likely to develop multidrug-resistant tuberculosis (OR 3.21, 95%CI=1.59-6.52). Multidrug-resistance was associated with inadequacy of treatment (OR 2.56, 95%CI=2.03-3.23). Failure of sputum conversion at the end of 2 months of treatment was detected to be the best predictor of multidrug-resistant tuberculosis (OR 11.82, 95% CI=4.61-30.33), followed by treatment with non Directly Observed Treatment Short course regimen and high labor intensive occupations like agriculture, production and transport. The risk factors of multidrug-resistant tuberculosis warrant much improvement in the effective implementation of control programs. Ibrahim Med. Coll. J. 2009; 3(1): 29-33http://www.imcjms.com/registration/journal_full_text/135TuberculosisMDR TB |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Md Nurul Amin Md Anisur Rahman Meerjady Sabrina Flora Md Abul Kalam Azad |
spellingShingle |
Md Nurul Amin Md Anisur Rahman Meerjady Sabrina Flora Md Abul Kalam Azad Factors associated with multidrug-resistant tuberculosis IMC Journal of Medical Science Tuberculosis MDR TB |
author_facet |
Md Nurul Amin Md Anisur Rahman Meerjady Sabrina Flora Md Abul Kalam Azad |
author_sort |
Md Nurul Amin |
title |
Factors associated with multidrug-resistant tuberculosis |
title_short |
Factors associated with multidrug-resistant tuberculosis |
title_full |
Factors associated with multidrug-resistant tuberculosis |
title_fullStr |
Factors associated with multidrug-resistant tuberculosis |
title_full_unstemmed |
Factors associated with multidrug-resistant tuberculosis |
title_sort |
factors associated with multidrug-resistant tuberculosis |
publisher |
Ibrahim Medical College |
series |
IMC Journal of Medical Science |
issn |
2519-1721 2519-1586 |
publishDate |
2009-01-01 |
description |
This case control study was conducted in selected centers of Dhaka City from March to July 2008 to determine the association of multidrug-resistant tuberculosis with the attributes related to treatment and socio-economic condition of tuberculosis patients. Sixty seven culture-proven multidrug-resistant tuberculosis cases and similar number of age and sex matched controls were selected purposively. Data were collected by face to face interview and documents’ review, using a pre tested structured questionnaire and a checklist. Multidrug-resistance was found to be associated with occupation (p=0.001) and residential status (p=0.001) of the tuberculosis patients. Tuberculosis patients who did not remain under directly observed treatment were 3 times more likely to develop multidrug-resistant tuberculosis (OR 3.21, 95%CI=1.59-6.52). Multidrug-resistance was associated with inadequacy of treatment (OR 2.56, 95%CI=2.03-3.23). Failure of sputum conversion at the end of 2 months of treatment was detected to be the best predictor of multidrug-resistant tuberculosis (OR 11.82, 95% CI=4.61-30.33), followed by treatment with non Directly Observed Treatment Short course regimen and high labor intensive occupations like agriculture, production and transport. The risk factors of multidrug-resistant tuberculosis warrant much improvement in the effective implementation of control programs.
Ibrahim Med. Coll. J. 2009; 3(1): 29-33 |
topic |
Tuberculosis MDR TB |
url |
http://www.imcjms.com/registration/journal_full_text/135 |
work_keys_str_mv |
AT mdnurulamin factorsassociatedwithmultidrugresistanttuberculosis AT mdanisurrahman factorsassociatedwithmultidrugresistanttuberculosis AT meerjadysabrinaflora factorsassociatedwithmultidrugresistanttuberculosis AT mdabulkalamazad factorsassociatedwithmultidrugresistanttuberculosis |
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1725377020592914432 |