Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread.
There is direct evidence for the spread of infectious diseases such as influenza, SARS, measles, and norovirus in locations where large groups of people gather at high densities e.g. theme parks, airports, etc. The mixing of susceptible and infectious individuals in these high people density man-mad...
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doaj-6975581d7d554591921e9386f1eb762d2021-03-03T21:59:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01157e023589110.1371/journal.pone.0235891Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread.Pierrot DerjanySirish NamilaeDahai LiuAshok SrinivasanThere is direct evidence for the spread of infectious diseases such as influenza, SARS, measles, and norovirus in locations where large groups of people gather at high densities e.g. theme parks, airports, etc. The mixing of susceptible and infectious individuals in these high people density man-made environments involves pedestrian movement which is generally not taken into account in modeling studies of disease dynamics. We address this problem through a multiscale model that combines pedestrian dynamics with stochastic infection spread models. The pedestrian dynamics model is utilized to generate the trajectories of motion and contacts between infected and susceptible individuals. We incorporate this information into a stochastic infection dynamics model with infection probability and contact radius as primary inputs. This generic model is applicable for several directly transmitted diseases by varying the input parameters related to infectivity and transmission mechanisms. Through this multiscale framework, we estimate the aggregate numbers and probabilities of newly infected people for different winding queue configurations. We find that the queue configuration has a significant impact on disease spread for a range of infection radii and transmission probabilities. We quantify the effectiveness of wall separators in suppressing the disease spread compared to rope separators. Further, we find that configurations with short aisles lower the infection spread when rope separators are used.https://doi.org/10.1371/journal.pone.0235891 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pierrot Derjany Sirish Namilae Dahai Liu Ashok Srinivasan |
spellingShingle |
Pierrot Derjany Sirish Namilae Dahai Liu Ashok Srinivasan Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. PLoS ONE |
author_facet |
Pierrot Derjany Sirish Namilae Dahai Liu Ashok Srinivasan |
author_sort |
Pierrot Derjany |
title |
Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. |
title_short |
Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. |
title_full |
Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. |
title_fullStr |
Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. |
title_full_unstemmed |
Multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. |
title_sort |
multiscale model for the optimal design of pedestrian queues to mitigate infectious disease spread. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2020-01-01 |
description |
There is direct evidence for the spread of infectious diseases such as influenza, SARS, measles, and norovirus in locations where large groups of people gather at high densities e.g. theme parks, airports, etc. The mixing of susceptible and infectious individuals in these high people density man-made environments involves pedestrian movement which is generally not taken into account in modeling studies of disease dynamics. We address this problem through a multiscale model that combines pedestrian dynamics with stochastic infection spread models. The pedestrian dynamics model is utilized to generate the trajectories of motion and contacts between infected and susceptible individuals. We incorporate this information into a stochastic infection dynamics model with infection probability and contact radius as primary inputs. This generic model is applicable for several directly transmitted diseases by varying the input parameters related to infectivity and transmission mechanisms. Through this multiscale framework, we estimate the aggregate numbers and probabilities of newly infected people for different winding queue configurations. We find that the queue configuration has a significant impact on disease spread for a range of infection radii and transmission probabilities. We quantify the effectiveness of wall separators in suppressing the disease spread compared to rope separators. Further, we find that configurations with short aisles lower the infection spread when rope separators are used. |
url |
https://doi.org/10.1371/journal.pone.0235891 |
work_keys_str_mv |
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