Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment
Elaeis guineensis of the Arecaceae family is widely used in the traditional medicine of societies in West Africa for treating various ailments. To validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied. The results showed that E. guineensis leaf extrac...
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2011-12-01
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doaj-697dc5c9e34d4711ab4ba85afd095e352020-11-24T23:27:18ZengMDPI AGInternational Journal of Molecular Sciences1422-00672011-12-0113133634710.3390/ijms13010336Wound Healing Activity of Elaeis guineensis Leaf Extract OintmentSreenivasan SasidharanLachimanan Yoga LathaSelvarasoo LogeswaranElaeis guineensis of the Arecaceae family is widely used in the traditional medicine of societies in West Africa for treating various ailments. To validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied. The results showed that E. guineensis leaf extract had potent wound healing capacity as evident from the better wound closure (P < 0.05), improved tissue regeneration at the wound site, and supporting histopathological parameters pertaining to wound healing. Matrix metalloproteinases expression correlated well with the results thus confirming efficacy of E. guineensis in the treatment of the wound. E. guineensis accelerated wound healing in rats, thus supporting its traditional use. The result of this study suggested that, used efficiently, oil palm leaf extract is a renewable resource with wound healing properties.http://www.mdpi.com/1422-0067/13/1/336/Elaeis guineensiswound healing activitymatrix metalloproteinasesgelatin zymography |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sreenivasan Sasidharan Lachimanan Yoga Latha Selvarasoo Logeswaran |
spellingShingle |
Sreenivasan Sasidharan Lachimanan Yoga Latha Selvarasoo Logeswaran Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment International Journal of Molecular Sciences Elaeis guineensis wound healing activity matrix metalloproteinases gelatin zymography |
author_facet |
Sreenivasan Sasidharan Lachimanan Yoga Latha Selvarasoo Logeswaran |
author_sort |
Sreenivasan Sasidharan |
title |
Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment |
title_short |
Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment |
title_full |
Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment |
title_fullStr |
Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment |
title_full_unstemmed |
Wound Healing Activity of Elaeis guineensis Leaf Extract Ointment |
title_sort |
wound healing activity of elaeis guineensis leaf extract ointment |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2011-12-01 |
description |
Elaeis guineensis of the Arecaceae family is widely used in the traditional medicine of societies in West Africa for treating various ailments. To validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied. The results showed that E. guineensis leaf extract had potent wound healing capacity as evident from the better wound closure (P < 0.05), improved tissue regeneration at the wound site, and supporting histopathological parameters pertaining to wound healing. Matrix metalloproteinases expression correlated well with the results thus confirming efficacy of E. guineensis in the treatment of the wound. E. guineensis accelerated wound healing in rats, thus supporting its traditional use. The result of this study suggested that, used efficiently, oil palm leaf extract is a renewable resource with wound healing properties. |
topic |
Elaeis guineensis wound healing activity matrix metalloproteinases gelatin zymography |
url |
http://www.mdpi.com/1422-0067/13/1/336/ |
work_keys_str_mv |
AT sreenivasansasidharan woundhealingactivityofelaeisguineensisleafextractointment AT lachimananyogalatha woundhealingactivityofelaeisguineensisleafextractointment AT selvarasoologeswaran woundhealingactivityofelaeisguineensisleafextractointment |
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1725552510881497088 |