An abundant quiescent stem cell population in Drosophila Malpighian tubules protects principal cells from kidney stones
Adult Drosophila Malpighian tubules have low rates of cell turnover but are vulnerable to damage caused by stones, like their mammalian counterparts, kidneys. We show that Drosophilarenal stem cells (RSCs) in the ureter and lower tubules comprise a unique, unipotent regenerative compartment. RSCs re...
Main Authors: | Chenhui Wang, Allan C Spradling |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/54096 |
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