Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel
Abstract Objective To evaluate whether patients with COVID-19 who have tested re-positive with the PCR test for the SARS-CoV-2 virus are infectious is a challenge in the current circumstances. A follow-up survey was conducted with healthcare personnel (HCP) who were exposed to a patient whose PCR te...
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doaj-69940f0f3d70428a856a645f61cd68d32020-11-25T04:03:22ZengBMCBMC Research Notes1756-05002020-11-011311410.1186/s13104-020-05365-yAssessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnelYoshihiko Ogawa0Koji Nishida1Iwao Gohma2Kei Kasahara3Hisakazu Yano4Department of Infectious Diseases, Sakai City Medical CenterTreatment Team for COVID-19, Sakai City Medical CenterTreatment Team for COVID-19, Sakai City Medical CenterCenter for Infectious Diseases, Nara Medical UniversityDepartment of Microbiology and Infectious Diseases, Nara Medical UniversityAbstract Objective To evaluate whether patients with COVID-19 who have tested re-positive with the PCR test for the SARS-CoV-2 virus are infectious is a challenge in the current circumstances. A follow-up survey was conducted with healthcare personnel (HCP) who were exposed to a patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative PCR results. Results We studied a total of 15 HCP who had contact exposures (15/15) and aerosol exposures (7/15). None of them tested positive for IgG against SARS-CoV-2 on blood examination. None of them had any symptoms during 10 days of active isolation. All PCR tests conducted using the nasopharyngeal swabs collected from the HCP on day 10 were negative. No apparent infection was found in any of the HCP who had contact exposure with and/or aerosol exposure to the patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative results of PCR tests for SARS-CoV-2. Clinical trial: Trial Registration: No. 170, approved June 10th, 2020 by the ethics committee of Sakai City Medical Center.http://link.springer.com/article/10.1186/s13104-020-05365-ySARS-CoV-2COVID-19Healthcare personnelPCR re-positive |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yoshihiko Ogawa Koji Nishida Iwao Gohma Kei Kasahara Hisakazu Yano |
spellingShingle |
Yoshihiko Ogawa Koji Nishida Iwao Gohma Kei Kasahara Hisakazu Yano Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel BMC Research Notes SARS-CoV-2 COVID-19 Healthcare personnel PCR re-positive |
author_facet |
Yoshihiko Ogawa Koji Nishida Iwao Gohma Kei Kasahara Hisakazu Yano |
author_sort |
Yoshihiko Ogawa |
title |
Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_short |
Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_full |
Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_fullStr |
Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_full_unstemmed |
Assessing the effects of exposure to a SARS-CoV-2 re-positive patient in healthcare personnel |
title_sort |
assessing the effects of exposure to a sars-cov-2 re-positive patient in healthcare personnel |
publisher |
BMC |
series |
BMC Research Notes |
issn |
1756-0500 |
publishDate |
2020-11-01 |
description |
Abstract Objective To evaluate whether patients with COVID-19 who have tested re-positive with the PCR test for the SARS-CoV-2 virus are infectious is a challenge in the current circumstances. A follow-up survey was conducted with healthcare personnel (HCP) who were exposed to a patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative PCR results. Results We studied a total of 15 HCP who had contact exposures (15/15) and aerosol exposures (7/15). None of them tested positive for IgG against SARS-CoV-2 on blood examination. None of them had any symptoms during 10 days of active isolation. All PCR tests conducted using the nasopharyngeal swabs collected from the HCP on day 10 were negative. No apparent infection was found in any of the HCP who had contact exposure with and/or aerosol exposure to the patient whose PCR test results for SARS-CoV-2 were re-positive 18 days after the initial confirmation of negative results of PCR tests for SARS-CoV-2. Clinical trial: Trial Registration: No. 170, approved June 10th, 2020 by the ethics committee of Sakai City Medical Center. |
topic |
SARS-CoV-2 COVID-19 Healthcare personnel PCR re-positive |
url |
http://link.springer.com/article/10.1186/s13104-020-05365-y |
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AT yoshihikoogawa assessingtheeffectsofexposuretoasarscov2repositivepatientinhealthcarepersonnel AT kojinishida assessingtheeffectsofexposuretoasarscov2repositivepatientinhealthcarepersonnel AT iwaogohma assessingtheeffectsofexposuretoasarscov2repositivepatientinhealthcarepersonnel AT keikasahara assessingtheeffectsofexposuretoasarscov2repositivepatientinhealthcarepersonnel AT hisakazuyano assessingtheeffectsofexposuretoasarscov2repositivepatientinhealthcarepersonnel |
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