The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials
In a previous study, we found that Primo vessels generate different action potentials in smooth muscles, but this study compared the pulse shape to distinguish the two tissues. Thus, a more sophisticated extracellular experiment was performed in this study using an acetylcholine injection; we then o...
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doaj-6994452b4f1c498b97629ab6abe893222020-11-24T22:27:54ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882013-01-01201310.1155/2013/657969657969The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action PotentialsSeong Jin Cho0Jaekwan Lim1Sun Hee Yeon2O. Sang Kwon3Kwang-Ho Choi4Sun-Mi Choi5Yeon-Hee Ryu6Acupuncture, Moxibustion, and Meridian Research Group, Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of KoreaAdvanced Institutes of Convergence Technology, Seoul National University, Suwon, Republic of KoreaAcupuncture, Moxibustion, and Meridian Research Group, Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of KoreaAcupuncture, Moxibustion, and Meridian Research Group, Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of KoreaAcupuncture, Moxibustion, and Meridian Research Group, Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of KoreaAcupuncture, Moxibustion, and Meridian Research Group, Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of KoreaAcupuncture, Moxibustion, and Meridian Research Group, Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of KoreaIn a previous study, we found that Primo vessels generate different action potentials in smooth muscles, but this study compared the pulse shape to distinguish the two tissues. Thus, a more sophisticated extracellular experiment was performed in this study using an acetylcholine injection; we then observed changes in the amplitude, FWHM (full width at half maximum), and period to explore Primo vessel function. A third type of pulse was recorded for Primo vessels. We observed fast depolarizing and repolarizing phases for this pulse. Further, its FWHM was 30 ms between smooth muscles and neurons. Acetylcholine affected only the period. The amplitude and FWHM were consistent after injection. Primo-vessels generated action potentials at twice the frequency after injection. From the results, we speculate that Primo-vessels perform a role in transferring signals in a different manner, which may be relevant for acupuncture treatment.http://dx.doi.org/10.1155/2013/657969 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Seong Jin Cho Jaekwan Lim Sun Hee Yeon O. Sang Kwon Kwang-Ho Choi Sun-Mi Choi Yeon-Hee Ryu |
spellingShingle |
Seong Jin Cho Jaekwan Lim Sun Hee Yeon O. Sang Kwon Kwang-Ho Choi Sun-Mi Choi Yeon-Hee Ryu The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials Evidence-Based Complementary and Alternative Medicine |
author_facet |
Seong Jin Cho Jaekwan Lim Sun Hee Yeon O. Sang Kwon Kwang-Ho Choi Sun-Mi Choi Yeon-Hee Ryu |
author_sort |
Seong Jin Cho |
title |
The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials |
title_short |
The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials |
title_full |
The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials |
title_fullStr |
The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials |
title_full_unstemmed |
The Characteristics of Action Potentials in Primo Vessels and the Effects of Acetylcholine Injection to the Action Potentials |
title_sort |
characteristics of action potentials in primo vessels and the effects of acetylcholine injection to the action potentials |
publisher |
Hindawi Limited |
series |
Evidence-Based Complementary and Alternative Medicine |
issn |
1741-427X 1741-4288 |
publishDate |
2013-01-01 |
description |
In a previous study, we found that Primo vessels generate different action potentials in smooth muscles, but this study compared the pulse shape to distinguish the two tissues. Thus, a more sophisticated extracellular experiment was performed in this study using an acetylcholine injection; we then observed changes in the amplitude, FWHM (full width at half maximum), and period to explore Primo vessel function. A third type of pulse was recorded for Primo vessels. We observed fast depolarizing and repolarizing phases for this pulse. Further, its FWHM was 30 ms between smooth muscles and neurons. Acetylcholine affected only the period. The amplitude and FWHM were consistent after injection. Primo-vessels generated action potentials at twice the frequency after injection. From the results, we speculate that Primo-vessels perform a role in transferring signals in a different manner, which may be relevant for acupuncture treatment. |
url |
http://dx.doi.org/10.1155/2013/657969 |
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