IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats

IR-61 Improves Voiding Function via Mitochondrial Protection in Diabetic Rats

Diabetic bladder dysfunction (DBD) afflicts nearly half of diabetic patients, but effective treatment is lacking. In this study, IR-61, a novel heptamethine cyanine dye with potential antioxidant effects, was investigated to determine whether it can alleviate DBD. Rats were intraperitoneally injecte...

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Bibliographic Details
Main Authors: Jianwu Wang, Linyong Dai, Xiaofeng Yue, Chongxing Shen, Tong Li, Lei Long, Yi Zhi, Yawei Wang, Gufang Shen, Chunmeng Shi, Yunsheng Liu, Qiang Fang, Weibing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
bladder smooth muscle cells
diabetic bladder dysfunction
IR-61
mitochondria
nuclear factor erythroid 2-related factor 2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.608637/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.608637/full

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