Prediction and identification of synergistic compound combinations against pancreatic cancer cells
Summary: Resistance to current therapies is common for pancreatic cancer and hence novel treatment options are urgently needed. In this work, we developed and validated a computational method to select synergistic compound combinations based on transcriptomic profiles from both the disease and compo...
Main Authors: | Yasaman KalantarMotamedi, Ran Joo Choi, Siang-Boon Koh, Jo L. Bramhall, Tai-Ping Fan, Andreas Bender |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221010488 |
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