Rare genetic variants prioritize molecular pathways for semaphorin interactions in Alzheimer’s disease patients

Rare genetic variants prioritize molecular pathways for semaphorin interactions in Alzheimer’s disease patients

Contemporary genetic methods have not yet solved the ‘missing heritability’ problem of complex diseases such as Alzheimer’s disease (AD). The impact of rare or less common variation on human complex diseases and traits remains to date barely investigated. In this study rare population variants detec...

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Bibliographic Details
Main Authors: Lubomir Balabanski, Dimitar Serbezov, Maya Atanasoska, Sena Karachanak-Yankova, Savina Hadjidekova, Dragomira Nikolova, Olga Boyanova, Rada Staneva, Radoslava Vazharova, Marta Mihailova, Vera Damyanova, Desislava Nesheva, Diana Belejanska, Shima Mehrabian, Lachezar Traykov, Draga Toncheva
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
alzheimer’s disease
molecular pathways
whole-exome sequencing
Online Access:http://dx.doi.org/10.1080/13102818.2021.1964382

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