Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity
To study the effect of high dose ginger on plasma testosterone and leutinising hormone levels in male rats after lead induced toxicity Methods: In this quasi experimental study, 30 adult male Sprague Dawley rats were divided in two equal groups. Group A was given 0.3% lead acetate in drinking water...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Rawalpindi Medical University
2017-03-01
|
Series: | Journal of Rawalpindi Medical College |
Subjects: | |
Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/119 |
id |
doaj-69f78b21a4944c96b22450e088ced9a0 |
---|---|
record_format |
Article |
spelling |
doaj-69f78b21a4944c96b22450e088ced9a02020-11-25T03:37:45ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702017-03-01211Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced ToxicityFatima Riaz0Department of Physiology, Islamic International Dental College, Riphah International University, Islamabad; To study the effect of high dose ginger on plasma testosterone and leutinising hormone levels in male rats after lead induced toxicity Methods: In this quasi experimental study, 30 adult male Sprague Dawley rats were divided in two equal groups. Group A was given 0.3% lead acetate in drinking water and kept as lead control while the Group B was given a dose of 1.5gm/kg body weight ginger orally along with 0.3% lead for 42 consecutive days. Rats were then sacrificed and serum testosterone and LH levels were analyzed using ELISA technique. Data was expressed as mean±SD. P-values <0.05 were considered as statistically significant. Results: At the end of 42 days, mean serum testosterone level in Group A (control Group) was 2.2667± 0.45617ng/ml as compared to Group B (Experimental Group) 2.2667 ± 0.45617ng/ml and showed statistically insignificant change(p>0.05). Comparison of mean serum LH levels in Group A (5.3200 ± 0.72526ng/ml)revealed statistically insignificant difference (p>0.05) as compared to Group B (5.7467 ± 0.70190ng/ml). Conclusion: High dose ginger (>1gm/kg body weight) failed to enhance the suppressed testosterone level due to lead toxicity in male rats https://www.journalrmc.com/index.php/JRMC/article/view/119Lead toxicityhigh dose gingerplasma testosterone and LH levels |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fatima Riaz |
spellingShingle |
Fatima Riaz Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity Journal of Rawalpindi Medical College Lead toxicity high dose ginger plasma testosterone and LH levels |
author_facet |
Fatima Riaz |
author_sort |
Fatima Riaz |
title |
Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity |
title_short |
Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity |
title_full |
Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity |
title_fullStr |
Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity |
title_full_unstemmed |
Effect of High Dose Ginger on Plasma Testosterone and Leutinising Hormone Levels in Male Rats after Lead Induced Toxicity |
title_sort |
effect of high dose ginger on plasma testosterone and leutinising hormone levels in male rats after lead induced toxicity |
publisher |
Rawalpindi Medical University |
series |
Journal of Rawalpindi Medical College |
issn |
1683-3562 1683-3570 |
publishDate |
2017-03-01 |
description |
To study the effect of high dose
ginger on plasma testosterone and leutinising
hormone levels in male rats after lead induced
toxicity
Methods: In this quasi experimental study, 30
adult male Sprague Dawley rats were divided in two
equal groups. Group A was given 0.3% lead acetate
in drinking water and kept as lead control while the
Group B was given a dose of 1.5gm/kg body weight
ginger orally along with 0.3% lead for 42 consecutive
days. Rats were then sacrificed and serum
testosterone and LH levels were analyzed using
ELISA technique. Data was expressed as mean±SD.
P-values <0.05 were considered as statistically
significant.
Results: At the end of 42 days, mean serum
testosterone level in Group A (control Group) was
2.2667± 0.45617ng/ml as compared to Group B
(Experimental Group) 2.2667 ± 0.45617ng/ml and
showed statistically insignificant change(p>0.05).
Comparison of mean serum LH levels in Group A
(5.3200 ± 0.72526ng/ml)revealed statistically
insignificant difference (p>0.05) as compared to
Group B (5.7467 ± 0.70190ng/ml).
Conclusion: High dose ginger (>1gm/kg body
weight) failed to enhance the suppressed
testosterone level due to lead toxicity in male rats
|
topic |
Lead toxicity high dose ginger plasma testosterone and LH levels |
url |
https://www.journalrmc.com/index.php/JRMC/article/view/119 |
work_keys_str_mv |
AT fatimariaz effectofhighdosegingeronplasmatestosteroneandleutinisinghormonelevelsinmaleratsafterleadinducedtoxicity |
_version_ |
1724544161000980480 |