The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats

Introduction: This study evaluated the protective effects of 2 commercial formats of Ginkgo biloba on motor alterations induced by cassava (Manihot esculenta Crantz) juice consumption in male Wistar rats. Methods: The effects were evaluated with the open field and swim tests at 0, 7, 14, 21, and 28...

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Main Authors: E. Rivadeneyra-Domínguez, A. Vázquez-Luna, J.F. Rodríguez-Landa, C.V. Mérida-Portilla, R. Díaz-Sobac
Format: Article
Language:English
Published: Elsevier España 2017-10-01
Series:Neurología (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2173580817301244
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spelling doaj-6a04a7d4ee6845eb91b368d56e9b47352020-11-25T02:37:43ZengElsevier EspañaNeurología (English Edition)2173-58082017-10-01328516522The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar ratsE. Rivadeneyra-Domínguez0A. Vázquez-Luna1J.F. Rodríguez-Landa2C.V. Mérida-Portilla3R. Díaz-Sobac4Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, Mexico; Corresponding author.Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, Mexico; Laboratorio de Biología y Química Molecular de Frutas, Instituto de Ciencias Básicas, Universidad Veracruzana, Xalapa, Veracruz, MexicoLaboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, Mexico; Instituto de Neuroetología, Universidad Veracruzana, Xalapa, Veracruz, MexicoLaboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, MexicoLaboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, Mexico; Laboratorio de Biología y Química Molecular de Frutas, Instituto de Ciencias Básicas, Universidad Veracruzana, Xalapa, Veracruz, MexicoIntroduction: This study evaluated the protective effects of 2 commercial formats of Ginkgo biloba on motor alterations induced by cassava (Manihot esculenta Crantz) juice consumption in male Wistar rats. Methods: The effects were evaluated with the open field and swim tests at 0, 7, 14, 21, and 28 days of treatment, one hour after administering the product. Results: Compared to controls, open field crossings increased after day 21 of cassava juice consumption, and lateral swimming in the swim test was reported after day 7. Conclusion: Ginkgo biloba extracts prevented motor alterations associated with cassava juice consumption, probably due to the flavonoid content in both formats of Ginkgo biloba. Resumen: Introducción: Se evaluó el efecto protector de 2 presentaciones comerciales de Ginkgo biloba sobre las alteraciones motoras inducidas por el consumo de jugo de yuca (Manihot esculenta Crantz) en ratas macho Wistar. Método: Los efectos se evaluaron en las pruebas de campo abierto y nado a los 0, 7, 14, 21 y 28 días de tratamiento, una hora después de la administración correspondiente. Resultados: A partir del día 21 del consumo de jugo de yuca incrementó el número de cuadros cruzados en campo abierto y, en la prueba de nado, produjo el nado lateral a partir del día 7, con respecto al grupo control. Conclusión: Los extractos de Ginkgo biloba previnieron las alteraciones motoras asociadas al consumo de jugo de yuca, probablemente por el contenido de flavonoides presentes en ambas presentaciones de Ginkgo biloba. Keywords: Cassava, Ginkgo biloba, Lateral swim, Motor alterations, Linamarin, Konzo, Palabras clave: Yuca, Ginkgo biloba, Nado lateral, Alteración motora, Linamarina, Konzohttp://www.sciencedirect.com/science/article/pii/S2173580817301244
collection DOAJ
language English
format Article
sources DOAJ
author E. Rivadeneyra-Domínguez
A. Vázquez-Luna
J.F. Rodríguez-Landa
C.V. Mérida-Portilla
R. Díaz-Sobac
spellingShingle E. Rivadeneyra-Domínguez
A. Vázquez-Luna
J.F. Rodríguez-Landa
C.V. Mérida-Portilla
R. Díaz-Sobac
The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats
Neurología (English Edition)
author_facet E. Rivadeneyra-Domínguez
A. Vázquez-Luna
J.F. Rodríguez-Landa
C.V. Mérida-Portilla
R. Díaz-Sobac
author_sort E. Rivadeneyra-Domínguez
title The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats
title_short The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats
title_full The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats
title_fullStr The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats
title_full_unstemmed The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats
title_sort protective effect of two commercial formats of ginkgo biloba on motor alterations induced by cassava juice (manihot esculenta crantz) in wistar rats
publisher Elsevier España
series Neurología (English Edition)
issn 2173-5808
publishDate 2017-10-01
description Introduction: This study evaluated the protective effects of 2 commercial formats of Ginkgo biloba on motor alterations induced by cassava (Manihot esculenta Crantz) juice consumption in male Wistar rats. Methods: The effects were evaluated with the open field and swim tests at 0, 7, 14, 21, and 28 days of treatment, one hour after administering the product. Results: Compared to controls, open field crossings increased after day 21 of cassava juice consumption, and lateral swimming in the swim test was reported after day 7. Conclusion: Ginkgo biloba extracts prevented motor alterations associated with cassava juice consumption, probably due to the flavonoid content in both formats of Ginkgo biloba. Resumen: Introducción: Se evaluó el efecto protector de 2 presentaciones comerciales de Ginkgo biloba sobre las alteraciones motoras inducidas por el consumo de jugo de yuca (Manihot esculenta Crantz) en ratas macho Wistar. Método: Los efectos se evaluaron en las pruebas de campo abierto y nado a los 0, 7, 14, 21 y 28 días de tratamiento, una hora después de la administración correspondiente. Resultados: A partir del día 21 del consumo de jugo de yuca incrementó el número de cuadros cruzados en campo abierto y, en la prueba de nado, produjo el nado lateral a partir del día 7, con respecto al grupo control. Conclusión: Los extractos de Ginkgo biloba previnieron las alteraciones motoras asociadas al consumo de jugo de yuca, probablemente por el contenido de flavonoides presentes en ambas presentaciones de Ginkgo biloba. Keywords: Cassava, Ginkgo biloba, Lateral swim, Motor alterations, Linamarin, Konzo, Palabras clave: Yuca, Ginkgo biloba, Nado lateral, Alteración motora, Linamarina, Konzo
url http://www.sciencedirect.com/science/article/pii/S2173580817301244
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