Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization
Abstract Background The purpose of this study was to quantify cognitive deficits in severe anorexia nervosa (AN) before and after medical stabilization. Methods This was a prospective study of 40 females between the ages of 18 and 50 admitted to a medical stabilization unit with severe AN (%IBW <...
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doaj-6a059290999740e6a6423a0a2b6744142020-11-25T03:35:35ZengBMCJournal of Eating Disorders2050-29742020-07-018111010.1186/s40337-020-00312-5Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilizationMelanie Rylander0Gillian Taylor1Susan Bennett2Christopher Pierce3Angela Keniston4Philip S. Mehler5Departments of Internal Medicine and Psychiatry, Denver Health Medical Center, University of Colorado School of MedicineDepartment of Psychiatry, Denver Health Medical Center, University of Colorado School of MedicineDepartment of Psychiatry, Denver Health Medical Center, University of Colorado School of MedicineDepartment of Psychiatry, Denver Health Medical Center, University of Colorado School of MedicineDepartment of Internal Medicine, University of Colorado School of MedicineACUTE Center for Eating Disorders, Denver Health Medical Center, University of Colorado School of MedicineAbstract Background The purpose of this study was to quantify cognitive deficits in severe anorexia nervosa (AN) before and after medical stabilization. Methods This was a prospective study of 40 females between the ages of 18 and 50 admitted to a medical stabilization unit with severe AN (%IBW < 70). The primary outcome of the study was change in test scores on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) at baseline and after medical stabilization. Results There were no statistically significant differences in baseline RBANS scores between AN patients overall and controls (p = 0.0940). There was a statistically significant change in RBANS from baseline 94.1 + 12.7 to medical stabilization 97.1 + 10.6 (p = 0.0173), although notably both mean values fell within the average range. There were no significant differences in baseline RBANS scores between controls and AN-BP patients (p = 0.3320) but significant differences were found between controls and AN-R patients (p = 0.0434). Conclusions No baseline deficits in cognition were found in this sample of women with severe AN.http://link.springer.com/article/10.1186/s40337-020-00312-5Anorexia nervosaMalnutritionCognitionRefeedingStarved brain |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Melanie Rylander Gillian Taylor Susan Bennett Christopher Pierce Angela Keniston Philip S. Mehler |
spellingShingle |
Melanie Rylander Gillian Taylor Susan Bennett Christopher Pierce Angela Keniston Philip S. Mehler Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization Journal of Eating Disorders Anorexia nervosa Malnutrition Cognition Refeeding Starved brain |
author_facet |
Melanie Rylander Gillian Taylor Susan Bennett Christopher Pierce Angela Keniston Philip S. Mehler |
author_sort |
Melanie Rylander |
title |
Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization |
title_short |
Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization |
title_full |
Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization |
title_fullStr |
Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization |
title_full_unstemmed |
Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization |
title_sort |
evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization |
publisher |
BMC |
series |
Journal of Eating Disorders |
issn |
2050-2974 |
publishDate |
2020-07-01 |
description |
Abstract Background The purpose of this study was to quantify cognitive deficits in severe anorexia nervosa (AN) before and after medical stabilization. Methods This was a prospective study of 40 females between the ages of 18 and 50 admitted to a medical stabilization unit with severe AN (%IBW < 70). The primary outcome of the study was change in test scores on the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) at baseline and after medical stabilization. Results There were no statistically significant differences in baseline RBANS scores between AN patients overall and controls (p = 0.0940). There was a statistically significant change in RBANS from baseline 94.1 + 12.7 to medical stabilization 97.1 + 10.6 (p = 0.0173), although notably both mean values fell within the average range. There were no significant differences in baseline RBANS scores between controls and AN-BP patients (p = 0.3320) but significant differences were found between controls and AN-R patients (p = 0.0434). Conclusions No baseline deficits in cognition were found in this sample of women with severe AN. |
topic |
Anorexia nervosa Malnutrition Cognition Refeeding Starved brain |
url |
http://link.springer.com/article/10.1186/s40337-020-00312-5 |
work_keys_str_mv |
AT melanierylander evaluationofcognitivefunctioninpatientswithsevereanorexianervosabeforeandaftermedicalstabilization AT gilliantaylor evaluationofcognitivefunctioninpatientswithsevereanorexianervosabeforeandaftermedicalstabilization AT susanbennett evaluationofcognitivefunctioninpatientswithsevereanorexianervosabeforeandaftermedicalstabilization AT christopherpierce evaluationofcognitivefunctioninpatientswithsevereanorexianervosabeforeandaftermedicalstabilization AT angelakeniston evaluationofcognitivefunctioninpatientswithsevereanorexianervosabeforeandaftermedicalstabilization AT philipsmehler evaluationofcognitivefunctioninpatientswithsevereanorexianervosabeforeandaftermedicalstabilization |
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