Innovative Approaches to Regenerate Enamel and Dentin
The process of tooth mineralization and the role of molecular control of cellular behavior during embryonic tooth development have attracted much attention the last few years. The knowledge gained from the research in these fields has improved the general understanding about the formation of dental...
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doaj-6a11c19cb9b64ffe8673ee0b322a56272020-11-24T22:39:47ZengHindawi LimitedInternational Journal of Dentistry1687-87281687-87362012-01-01201210.1155/2012/856470856470Innovative Approaches to Regenerate Enamel and DentinXanthippi Chatzistavrou0Silvana Papagerakis1Peter X. Ma2Petros Papagerakis3Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USADepartment of Otolaryngology, Head and Neck Surgery and Oncology, School of Medicine, University of Michigan, Ann Arbor, MI 48109, USADepartment of Biological and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USADepartment of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USAThe process of tooth mineralization and the role of molecular control of cellular behavior during embryonic tooth development have attracted much attention the last few years. The knowledge gained from the research in these fields has improved the general understanding about the formation of dental tissues and the entire tooth and set the basis for teeth regeneration. Tissue engineering using scaffold and cell aggregate methods has been considered to produce bioengineered dental tissues, while dental stem/progenitor cells, which can differentiate into dental cell lineages, have been also introduced into the field of tooth mineralization and regeneration. Some of the main strategies for making enamel, dentin, and complex tooth-like structures are presented in this paper. However, there are still significant barriers that obstruct such strategies to move into the regular clinic practice, and these should be overcome in order to have the regenerative dentistry as the important mean that can treat the consequences of tooth-related diseases.http://dx.doi.org/10.1155/2012/856470 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xanthippi Chatzistavrou Silvana Papagerakis Peter X. Ma Petros Papagerakis |
spellingShingle |
Xanthippi Chatzistavrou Silvana Papagerakis Peter X. Ma Petros Papagerakis Innovative Approaches to Regenerate Enamel and Dentin International Journal of Dentistry |
author_facet |
Xanthippi Chatzistavrou Silvana Papagerakis Peter X. Ma Petros Papagerakis |
author_sort |
Xanthippi Chatzistavrou |
title |
Innovative Approaches to Regenerate Enamel and Dentin |
title_short |
Innovative Approaches to Regenerate Enamel and Dentin |
title_full |
Innovative Approaches to Regenerate Enamel and Dentin |
title_fullStr |
Innovative Approaches to Regenerate Enamel and Dentin |
title_full_unstemmed |
Innovative Approaches to Regenerate Enamel and Dentin |
title_sort |
innovative approaches to regenerate enamel and dentin |
publisher |
Hindawi Limited |
series |
International Journal of Dentistry |
issn |
1687-8728 1687-8736 |
publishDate |
2012-01-01 |
description |
The process of tooth mineralization and the role of molecular control of cellular behavior during embryonic tooth development have attracted much attention the last few years. The knowledge gained from the research in these fields has improved the general understanding about the formation of dental tissues and the entire tooth and set the basis for teeth regeneration. Tissue engineering using scaffold and cell aggregate methods has been considered to produce bioengineered dental tissues, while dental stem/progenitor cells, which can differentiate into dental cell lineages, have been also introduced into the field of tooth mineralization and regeneration. Some of the main strategies for making enamel, dentin, and complex tooth-like structures are presented in this paper. However, there are still significant barriers that obstruct such strategies to move into the regular clinic practice, and these should be overcome in order to have the regenerative dentistry as the important mean that can treat the consequences of tooth-related diseases. |
url |
http://dx.doi.org/10.1155/2012/856470 |
work_keys_str_mv |
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1725707649923678208 |