Preventive Vaccination against Poliomyelitis: Modern View
Poliomyelitis is a typical anthroponosis, in natural conditions it infects only humans. The only effective strategy for combating the infection is preventive vaccination. The polio vaccine induces long-lasting humoral and local immunity. The article presents a brief history of polio vaccine developm...
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Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-12-01
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Series: | Биопрепараты: Профилактика, диагностика, лечение |
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Online Access: | https://www.biopreparations.ru/jour/article/view/195 |
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doaj-6a1270486237490eb88265112fefcdc92021-07-28T14:03:35ZrusMinistry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» Биопрепараты: Профилактика, диагностика, лечение2221-996X2619-11562018-12-0118423624210.30895/2221-996X-2018-18-4-236-242147Preventive Vaccination against Poliomyelitis: Modern ViewE. V. Karpova0К. А. Sarkisyan1A. A. Movsesyants2V. A. Merkulov3Scientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal Products; I. M. Sechenov First Moscow State Medical UniversityPoliomyelitis is a typical anthroponosis, in natural conditions it infects only humans. The only effective strategy for combating the infection is preventive vaccination. The polio vaccine induces long-lasting humoral and local immunity. The article presents a brief history of polio vaccine development, and compares live and inactivated vaccines currently licensed and used in Russia. It also dwells upon the benefits and shortcomings of each of these vaccines. The results of analysis demonstrated that all foreign-made and domestically-produced polio vaccines currently used in Russia meet international requirements in terms of main quality characteristics and comply with the WHO recommendations. The article looks into some issues arising from the use of live polio vaccine, in particular the development of vaccine-associated paralytic polio, and the appearance of vaccine-derived polioviruses. It reviews the main approaches of the current WHO polio eradication initiative, and summarises the outcomes of the 30-year period since the adoption of the Global Polio Eradication Initiative. The article describes the transition from live attenuated oral polio vaccine (types 1, 2 and 3) to bivalent vaccine (live attenuated oral polio vaccine, types 1 and 3). It discusses the necessity of using polio vaccines (both live and inactivated) at the final stage of polio eradication. The article presents the new National Immunisation Schedule.https://www.biopreparations.ru/jour/article/view/195poliomyelitispolio vaccinesinactivated polio vaccinelive oral polio vaccineimmune response to vaccinationimmunisation schedule |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
E. V. Karpova К. А. Sarkisyan A. A. Movsesyants V. A. Merkulov |
spellingShingle |
E. V. Karpova К. А. Sarkisyan A. A. Movsesyants V. A. Merkulov Preventive Vaccination against Poliomyelitis: Modern View Биопрепараты: Профилактика, диагностика, лечение poliomyelitis polio vaccines inactivated polio vaccine live oral polio vaccine immune response to vaccination immunisation schedule |
author_facet |
E. V. Karpova К. А. Sarkisyan A. A. Movsesyants V. A. Merkulov |
author_sort |
E. V. Karpova |
title |
Preventive Vaccination against Poliomyelitis: Modern View |
title_short |
Preventive Vaccination against Poliomyelitis: Modern View |
title_full |
Preventive Vaccination against Poliomyelitis: Modern View |
title_fullStr |
Preventive Vaccination against Poliomyelitis: Modern View |
title_full_unstemmed |
Preventive Vaccination against Poliomyelitis: Modern View |
title_sort |
preventive vaccination against poliomyelitis: modern view |
publisher |
Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» |
series |
Биопрепараты: Профилактика, диагностика, лечение |
issn |
2221-996X 2619-1156 |
publishDate |
2018-12-01 |
description |
Poliomyelitis is a typical anthroponosis, in natural conditions it infects only humans. The only effective strategy for combating the infection is preventive vaccination. The polio vaccine induces long-lasting humoral and local immunity. The article presents a brief history of polio vaccine development, and compares live and inactivated vaccines currently licensed and used in Russia. It also dwells upon the benefits and shortcomings of each of these vaccines. The results of analysis demonstrated that all foreign-made and domestically-produced polio vaccines currently used in Russia meet international requirements in terms of main quality characteristics and comply with the WHO recommendations. The article looks into some issues arising from the use of live polio vaccine, in particular the development of vaccine-associated paralytic polio, and the appearance of vaccine-derived polioviruses. It reviews the main approaches of the current WHO polio eradication initiative, and summarises the outcomes of the 30-year period since the adoption of the Global Polio Eradication Initiative. The article describes the transition from live attenuated oral polio vaccine (types 1, 2 and 3) to bivalent vaccine (live attenuated oral polio vaccine, types 1 and 3). It discusses the necessity of using polio vaccines (both live and inactivated) at the final stage of polio eradication. The article presents the new National Immunisation Schedule. |
topic |
poliomyelitis polio vaccines inactivated polio vaccine live oral polio vaccine immune response to vaccination immunisation schedule |
url |
https://www.biopreparations.ru/jour/article/view/195 |
work_keys_str_mv |
AT evkarpova preventivevaccinationagainstpoliomyelitismodernview AT kasarkisyan preventivevaccinationagainstpoliomyelitismodernview AT aamovsesyants preventivevaccinationagainstpoliomyelitismodernview AT vamerkulov preventivevaccinationagainstpoliomyelitismodernview |
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1721268700277899264 |