B Cell Competition for Restricted T Cell Help Suppresses Rare-Epitope Responses
Summary: The immune system responds preferentially to particular antigenic-epitopes contained within complex immunogens, such as proteins or microbes. This poorly understood phenomenon, termed “immunodominance,” remains an obstacle to achieving polyvalent immune responses against multiple antigenic-...
Main Authors: | Matthew Charles Woodruff, Eui Ho Kim, Wei Luo, Bali Pulendran |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-10-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718314591 |
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