Hibiscus sabdariffa polyphenol-enriched extract inhibits colon carcinoma metastasis associating with FAK and CD44/c-MET signaling

Hibiscus sabdariffa polyphenol-enriched extract inhibits colon carcinoma metastasis associating with FAK and CD44/c-MET signaling

Hibiscus sabdariffa extracts have multiple bioactivities. Here, we aimed to investigate the anti-metastatic effects of a polyphenol-enriched extract of Hibiscus sabdariffa (HPE) on colon cancer cells. We observed that HPE (≤3 mg/mL) significantly inhibited the cell migration and invasion of human co...

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Bibliographic Details
Main Authors: Chi-Chou Huang, Chia-Hung Hung, Ching-Chun Chen, Shao-Hsuan Kao, Chau-Jong Wang
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Functional Foods
Subjects:
Hibiscus sabdariffa polyphenols
Colorectal cancer cell
Metastasis
FAK
CD44
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618304134

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