Early Life Exposure to Environmentally Relevant Levels of Endocrine Disruptors Drive Multigenerational and Transgenerational Epigenetic Changes in a Fish Model

Early Life Exposure to Environmentally Relevant Levels of Endocrine Disruptors Drive Multigenerational and Transgenerational Epigenetic Changes in a Fish Model

The inland silverside, Menidia beryllina, is a euryhaline fish and a model organism in ecotoxicology. We previously showed that exposure to picomolar (ng/L) levels of endocrine disrupting chemicals (EDCs) can cause a variety of effects in M. beryllina, from changes in gene expression to phenotypic a...

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Bibliographic Details
Main Authors: Kaley M. Major, Bethany M. DeCourten, Jie Li, Monica Britton, Matthew L. Settles, Alvine C. Mehinto, Richard E. Connon, Susanne M. Brander
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Marine Science
Subjects:
epigenetics
Menidia beryllina
endocrine disruptors
transgenerational epigenetic inheritance
multigenerational exposure
DNA methylation
Online Access:https://www.frontiersin.org/article/10.3389/fmars.2020.00471/full

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