Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran
Among various trihalomethane (THM) compounds, chloroform is considered to be the main compound and was selected as an indicator of THMs in this study. This study aims to calculate and assess the lifetime cancer risks resulting from chloroform intakes of various exposure routes in Ilam’s urban dr...
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Hamadan University of Medical Sciences
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doaj-6a7b5cdab0aa46c68110c3d9ada1c23f2020-11-24T22:40:03ZengHamadan University of Medical SciencesAvicenna Journal of Environmental Health Engineering2423-45832423-45832016-03-01311710.17795/ajehe-5331 Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran Kamyar Arman0Ali Reza Pardakhti1Noushin Osoleddini2Mostafa Leili3Environmental Engineering Department, Faculty of Environment, University of Tehran, Tehran, IR IranEnvironmental Engineering Department, Faculty of Environment, University of Tehran, Tehran, IR IranApplied Chemistry Department, Faculty of Pharmaceutical Chemistry, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, IR IranDepartment of Environmental Health Engineering, School of Public Health and Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, IR Iran Among various trihalomethane (THM) compounds, chloroform is considered to be the main compound and was selected as an indicator of THMs in this study. This study aims to calculate and assess the lifetime cancer risks resulting from chloroform intakes of various exposure routes in Ilam’s urban drinking water. The samples were analyzed using a gas chromatograph equipped with a flame ionization detector (GC/FID). The results showed that average chloroform concentrations in different districts were between 20 and 30.3 μg/L, and the highest concentrations were detected in district 4 with a value of 32.2 μg/L. All water samples contained concentrations of chloroform below the standards of the world health organization (WHO) and the institute of standards and industrial research of Iran (ISIRI). Assessment of lifetime cancer risks was carried out using prediction models for different exposure routes, including ingestion, inhalation, and dermal routes for people living in Ilam city. The highest risk from chloroform seems to be from the oral ingestion route, followed by inhalation and dermal absorption. The maximum and minimum lifetime cancer risks were 6.59 × 10 - 6 and 5.95 × 10 - 6 in districts 4 and 3, respectively. It was also concluded that the average lifetime cancer risk was 6.26 × 10 - 6 in all districts. Based on the population data, the total number of expected lifetime cancer cases from exposure to chloroform is 1 for Ilam city.http://ajehe.com/en/articles/5331.htmlCancer Risk AssessmentChloroformTrihalomethanesDrinking WaterIlam |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kamyar Arman Ali Reza Pardakhti Noushin Osoleddini Mostafa Leili |
spellingShingle |
Kamyar Arman Ali Reza Pardakhti Noushin Osoleddini Mostafa Leili Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran Avicenna Journal of Environmental Health Engineering Cancer Risk Assessment Chloroform Trihalomethanes Drinking Water Ilam |
author_facet |
Kamyar Arman Ali Reza Pardakhti Noushin Osoleddini Mostafa Leili |
author_sort |
Kamyar Arman |
title |
Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran |
title_short |
Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran |
title_full |
Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran |
title_fullStr |
Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran |
title_full_unstemmed |
Cancer Risk Assessment From Multi-Exposure to Chloroform in Drinking Water of Ilam City, Iran |
title_sort |
cancer risk assessment from multi-exposure to chloroform in drinking water of ilam city, iran |
publisher |
Hamadan University of Medical Sciences |
series |
Avicenna Journal of Environmental Health Engineering |
issn |
2423-4583 2423-4583 |
publishDate |
2016-03-01 |
description |
Among various trihalomethane (THM) compounds, chloroform is considered to be the main compound and was selected as an indicator of THMs in this study. This study aims to calculate and assess the lifetime cancer risks resulting from chloroform intakes of various exposure routes in Ilam’s urban drinking water. The samples were analyzed using a gas chromatograph equipped with a flame ionization detector (GC/FID). The results showed that average chloroform concentrations in different districts were between 20 and 30.3 μg/L, and the highest concentrations were detected in district 4 with a value of 32.2 μg/L. All water samples contained concentrations of chloroform below the standards of the world health organization (WHO) and the institute of standards and industrial research of Iran (ISIRI). Assessment of lifetime cancer risks was carried out using prediction models for different exposure routes, including ingestion, inhalation, and dermal routes for people living in Ilam city. The highest risk from chloroform seems to be from the oral ingestion route, followed by inhalation and dermal absorption. The maximum and minimum lifetime cancer risks were 6.59 × 10 - 6 and 5.95 × 10 - 6 in districts 4 and 3, respectively. It was also concluded that the average lifetime cancer risk was 6.26 × 10 - 6 in all districts. Based on the population data, the total number of expected lifetime cancer cases from exposure to chloroform is 1 for Ilam city. |
topic |
Cancer Risk Assessment Chloroform Trihalomethanes Drinking Water Ilam |
url |
http://ajehe.com/en/articles/5331.html |
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