Repression of the Glucocorticoid Receptor Increases Hypoxic-Ischemic Brain Injury in the Male Neonatal Rat

Repression of the Glucocorticoid Receptor Increases Hypoxic-Ischemic Brain Injury in the Male Neonatal Rat

Hypoxic-ischemic encephalopathy (HIE) resulting from asphyxia is the most common cause of neonatal brain damage and results in significant neurological sequelae, including cerebral palsy. The current therapeutic interventions are extremely limited in improving neonatal outcomes. The present study te...

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Bibliographic Details
Main Authors: Katherine R. Knox-Concepcion, Johnny D. Figueroa, Richard E. Hartman, Yong Li, Lubo Zhang
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
glucocorticoid
glucocorticoid receptor
neuroprotection
Rice–Vannucci
neonatal
hypoxic-ischemic
encephalopathy
brain
neuroinflammation
functional outcomes
Online Access:https://www.mdpi.com/1422-0067/20/14/3493

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