Regulation of Mcl-1 Expression in Context to Bone Marrow Stromal Microenvironment in Chronic Lymphocytic Leukemia
A growing body of evidence suggests that the resistance of CLL cells to apoptosis is partly mediated through the interactions between leukemia cells and adjacent stromal cells residing in the lymphatic tissue or bone marrow microenvironment. Mcl-1, an anti-apoptotic protein that is associated with...
Main Authors: | Kumudha Balakrishnan, PhD, Jan A. Burger, Min Fu, Tejaswini Doifode, William G. Wierda, Varsha Gandhi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S147655861400150X |
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