Neuropsychiatric toxicity and cycloserine concentrations during treatment for multidrug-resistant tuberculosis

Neuropsychiatric toxicity and cycloserine concentrations during treatment for multidrug-resistant tuberculosis

Background: Cycloserine, or its structural analogue terizidone, has been associated with neuropsychiatric toxicity (psychosis, depression, and neuropathy). Prospective clinical data on the incidence of and risk factors for neuropsychiatric toxicity in TB patients treated with cycloserine are limited...

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Bibliographic Details
Main Authors: Richard Court, Chad M. Centner, Maxwell Chirehwa, Lubbe Wiesner, Paolo Denti, Nihal de Vries, Joseph Harding, Tawanda Gumbo, Gary Maartens, Helen McIlleron
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:International Journal of Infectious Diseases
Subjects:
Cycloserine
Terizidone
Pyridoxine
Pharmacokinetics
Neuropathy
Neuropsychiatric
Online Access:http://www.sciencedirect.com/science/article/pii/S120197122100206X

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http://www.sciencedirect.com/science/article/pii/S120197122100206X

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