Fixel-Based Analysis of White Matter Degeneration in Patients With Progressive Supranuclear Palsy or Multiple System Atrophy, as Compared to Parkinson's Disease

Fixel-Based Analysis of White Matter Degeneration in Patients With Progressive Supranuclear Palsy or Multiple System Atrophy, as Compared to Parkinson's Disease

Introduction: White matter degeneration may contribute to clinical symptoms of parkinsonism.Objective: We used fixel-based analysis (FBA) to compare the extent and patterns of white matter degeneration in different parkinsonian syndromes—including idiopathic Parkinson's disease (PD), multiple s...

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Main Authors: Thanh-Thao Nguyen, Jur-Shan Cheng, Yao-Liang Chen, Yu-Chun Lin, Chih-Chien Tsai, Chin-Song Lu, Yi-Hsin Weng, Yi-Ming Wu, Ngoc-Thanh Hoang, Jiun-Jie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
fixel-based analysis
white matter
Parkinson's disease
multiple system atrophy
progressive supranuclear palsy
diffusion weighted Imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.625874/full

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