Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles

An efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the react...

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Main Authors:	Sunil U. Tekale, Sushma S. Kauthale, Kavita M. Jadhav, Rajendra P. Pawar
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2013/840954

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spelling	doaj-6b079182875b4aef912f7416a60661e02020-11-24T23:25:47ZengHindawi LimitedJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/840954840954Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of PyranopyrazolesSunil U. Tekale0Sushma S. Kauthale1Kavita M. Jadhav2Rajendra P. Pawar3Department of Chemistry, Shri Muktanand College, Gangapur, Maharashtra 431 109, IndiaDepartment of Chemistry, Deogiri College, Station Road, Aurangabad, Maharashtra 431 005, IndiaDepartment of Chemistry, Deogiri College, Station Road, Aurangabad, Maharashtra 431 005, IndiaDepartment of Chemistry, Deogiri College, Station Road, Aurangabad, Maharashtra 431 005, IndiaAn efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the reaction medium, it serves as a green route for the synthesis of pyrano[2,3-c]pyrazoles. The advantages associated with the present protocol include nonchromatographic purification technique, use of recyclable heterogeneous nano-ZnO catalyst in aqueous medium, and short reaction time. It combines successfully the synergistic effect of green chemistry with nanocatalysis.http://dx.doi.org/10.1155/2013/840954
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Sunil U. Tekale Sushma S. Kauthale Kavita M. Jadhav Rajendra P. Pawar
spellingShingle	Sunil U. Tekale Sushma S. Kauthale Kavita M. Jadhav Rajendra P. Pawar Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles Journal of Chemistry
author_facet	Sunil U. Tekale Sushma S. Kauthale Kavita M. Jadhav Rajendra P. Pawar
author_sort	Sunil U. Tekale
title	Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
title_short	Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
title_full	Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
title_fullStr	Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
title_full_unstemmed	Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles
title_sort	nano-zno catalyzed green and efficient one-pot four-component synthesis of pyranopyrazoles
publisher	Hindawi Limited
series	Journal of Chemistry
issn	2090-9063 2090-9071
publishDate	2013-01-01
description	An efficient zinc oxide nanoparticle catalyzed one-pot, four-component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1,4-dihydropyrano[2,3-c]pyrazoles from aromatic aldehyde, malononitrile, ethyl acetoacetate, and hydrazine hydrate in aqueous medium is described. Since water was employed as the reaction medium, it serves as a green route for the synthesis of pyrano[2,3-c]pyrazoles. The advantages associated with the present protocol include nonchromatographic purification technique, use of recyclable heterogeneous nano-ZnO catalyst in aqueous medium, and short reaction time. It combines successfully the synergistic effect of green chemistry with nanocatalysis.
url	http://dx.doi.org/10.1155/2013/840954
work_keys_str_mv	AT sunilutekale nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles AT sushmaskauthale nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles AT kavitamjadhav nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles AT rajendrappawar nanoznocatalyzedgreenandefficientonepotfourcomponentsynthesisofpyranopyrazoles
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Nano-ZnO Catalyzed Green and Efficient One-Pot Four-Component Synthesis of Pyranopyrazoles

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