miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4.
microRNAs regulate the development of myogenic progenitors, and the formation of skeletal muscle fibers. However, the role miRNAs play in controlling the growth and adaptation of post-mitotic musculature is less clear. Here, we show that inhibition of the established pro-myogenic regulator miR-206 c...
Main Authors: | Catherine E Winbanks, Claudia Beyer, Adam Hagg, Hongwei Qian, Patricio V Sepulveda, Paul Gregorevic |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3759420?pdf=render |
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