DEVELOPMENT OF POLYCYSTIC OVARY SYNDROME IN A PATIENT SUFFERING FROM CLASSIC CONGENITAL ADRENAL CORTICAL HYPERPLASIA

• Main Authors: L. A. IVANOV, I. V. KOROL, YU. S. KOVALENKO, E. A. KOKOVA, A. V. MEZINOVA, Y. A. LIPNICKAYA
• Format: Article
• Language: Russian
• Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2017-12-01
• Series: Кубанский научный медицинский вестник
• Subjects: congenital adrenal cortical hyperplasia; polycystic ovary syndrome
• Online Access: https://ksma.elpub.ru/jour/article/view/943
• ISSN: 1608-6228; 2541-9544

Aim. To demostrate the complexity of the diagnosis and the consequences of the effect of insufficient hormone replacement therapy on the prognosis of the patient with the viril form of congenital adrenal cortical hyperplasia. Materials and methods. A retrospective analysis of anamnestic data, the course of the disease, laboratory and instrumental data and ongoing treatment throughout the life of the patient from birth to 23 years was carried out. Results. Since the diagnosis was established, frequent changes in periods of decompensation and compensation were observed, which led to the development of central and peripheral adenomatosis – adrenal hyperplasia, pituitary microadenoma, development of the polycystic ovary syndrome. Сonclusion. This case shows the importance of compensation for congenital adrenal cortical hyperplasia at all stages of ontogenesis to prevent the development of complications.