Characterization of Synthetic Tf2 as a Na<sub>V</sub>1.3 Selective Pharmacological Probe
Na<sub>V</sub>1.3 is a subtype of the voltage-gated sodium channel family. It has been implicated in the pathogenesis of neuropathic pain, although the contribution of this channel to neuronal excitability is not well understood. Tf2, a β-scorpion toxin previously identified from the ven...
Main Authors: | Mathilde R. Israel, Thomas S. Dash, Stefanie N. Bothe, Samuel D. Robinson, Jennifer R. Deuis, David J. Craik, Angelika Lampert, Irina Vetter, Thomas Durek |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/8/6/155 |
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