Analysis of bone mineral density and relevant factors in patients with type 1 diabetes
We investigated changes in bone mineral density (BMD) and relevant factors of BMD in patients with type 1 diabetes (T1D). A total of 47 patients with T1D and 40 healthy controls participated in this study. The waist-to-hip ratio (WHR) and body mass index (BMI) were calculated after physical...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
University of Belgrade, University of Novi Sad
2014-01-01
|
Series: | Archives of Biological Sciences |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641403091D.pdf |
id |
doaj-6b4e3c8641364e61ad5d4d6a642d26a6 |
---|---|
record_format |
Article |
spelling |
doaj-6b4e3c8641364e61ad5d4d6a642d26a62020-11-24T23:45:48ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46641821-43392014-01-016631091109610.2298/ABS1403091D0354-46641403091DAnalysis of bone mineral density and relevant factors in patients with type 1 diabetesDuan Peng0Tu Ping1Wu Heping2Ding Xun3Liu Jiang4Bo Deng5Department of Endocrinology, the Third Hospital of Nanchang/Nanchang Key Laboratory of Diabetes, Nanchang, ChinaDepartment of Endocrinology, the Third Hospital of Nanchang/Nanchang Key Laboratory of Diabetes, Nanchang, ChinaDepartment of Endocrinology, the Third Hospital of Nanchang/Nanchang Key Laboratory of Diabetes, Nanchang, ChinaDepartment of Endocrinology, the Third Hospital of Nanchang/Nanchang Key Laboratory of Diabetes, Nanchang, ChinaDepartment of Endocrinology, the Third Hospital of Nanchang/Nanchang Key Laboratory of Diabetes, Nanchang, ChinaDepartment of Endocrinology, the Third Hospital of Nanchang/Nanchang Key Laboratory of Diabetes, Nanchang, ChinaWe investigated changes in bone mineral density (BMD) and relevant factors of BMD in patients with type 1 diabetes (T1D). A total of 47 patients with T1D and 40 healthy controls participated in this study. The waist-to-hip ratio (WHR) and body mass index (BMI) were calculated after physical examination. The lumbar spine (L2-L4) BMD and left femoral neck BMD were examined. Blood samples were collected. The BMI, WHR, fasting C peptide (FCP), postprandial C peptide (2hCP), lumbar spine and left femoral neck BMD of the patients with T1D were significantly lower than those of healthy controls, while the fasting plasma glucose (FPG), postprandial plasma glucose (2hPG) and hemoglobin A1c (HbA1c) were higher (P <0.05). Duration of T1D and HbA1c were negatively correlated with lumbar spine and left femoral neck BMD. The FCP and 2hCP were positively correlated with lumbar spine and left femoral neck BMD.http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641403091D.pdfbone mineral densitybody mass indextype 1 diabetes |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Duan Peng Tu Ping Wu Heping Ding Xun Liu Jiang Bo Deng |
spellingShingle |
Duan Peng Tu Ping Wu Heping Ding Xun Liu Jiang Bo Deng Analysis of bone mineral density and relevant factors in patients with type 1 diabetes Archives of Biological Sciences bone mineral density body mass index type 1 diabetes |
author_facet |
Duan Peng Tu Ping Wu Heping Ding Xun Liu Jiang Bo Deng |
author_sort |
Duan Peng |
title |
Analysis of bone mineral density and relevant factors in patients with type 1 diabetes |
title_short |
Analysis of bone mineral density and relevant factors in patients with type 1 diabetes |
title_full |
Analysis of bone mineral density and relevant factors in patients with type 1 diabetes |
title_fullStr |
Analysis of bone mineral density and relevant factors in patients with type 1 diabetes |
title_full_unstemmed |
Analysis of bone mineral density and relevant factors in patients with type 1 diabetes |
title_sort |
analysis of bone mineral density and relevant factors in patients with type 1 diabetes |
publisher |
University of Belgrade, University of Novi Sad |
series |
Archives of Biological Sciences |
issn |
0354-4664 1821-4339 |
publishDate |
2014-01-01 |
description |
We investigated changes in bone mineral density (BMD) and relevant factors of
BMD in patients with type 1 diabetes (T1D). A total of 47 patients with T1D
and 40 healthy controls participated in this study. The waist-to-hip ratio
(WHR) and body mass index (BMI) were calculated after physical examination.
The lumbar spine (L2-L4) BMD and left femoral neck BMD were examined. Blood
samples were collected. The BMI, WHR, fasting C peptide (FCP), postprandial C
peptide (2hCP), lumbar spine and left femoral neck BMD of the patients with
T1D were significantly lower than those of healthy controls, while the
fasting plasma glucose (FPG), postprandial plasma glucose (2hPG) and
hemoglobin A1c (HbA1c) were higher (P <0.05). Duration of T1D and HbA1c were
negatively correlated with lumbar spine and left femoral neck BMD. The FCP
and 2hCP were positively correlated with lumbar spine and left femoral neck
BMD. |
topic |
bone mineral density body mass index type 1 diabetes |
url |
http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641403091D.pdf |
work_keys_str_mv |
AT duanpeng analysisofbonemineraldensityandrelevantfactorsinpatientswithtype1diabetes AT tuping analysisofbonemineraldensityandrelevantfactorsinpatientswithtype1diabetes AT wuheping analysisofbonemineraldensityandrelevantfactorsinpatientswithtype1diabetes AT dingxun analysisofbonemineraldensityandrelevantfactorsinpatientswithtype1diabetes AT liujiang analysisofbonemineraldensityandrelevantfactorsinpatientswithtype1diabetes AT bodeng analysisofbonemineraldensityandrelevantfactorsinpatientswithtype1diabetes |
_version_ |
1725495665326292992 |