Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture
Background:. Capsular contracture is a common complication after breast augmentation surgery. This study pathologically evaluated the soft-tissue response to surface modifications in both smooth and textured tissue expander prostheses. Methods:. Smooth tissue expanders and textured tissue expanders...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2017-07-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001403 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Erika Kuriyama, MD Hiroko Ochiai, MD, PhD Yoshikazu Inoue, MD, PhD Yoshiaki Sakamoto, MD, PhD Naoki Yamamoto, CMDT, PhD Toshiaki Utsumi, MD, PhD Kazuo Kishi, MD, PhD Takayuki Okumoto, MD, PhD Akihiro Matsuura, MD, PhD |
| spellingShingle |
Erika Kuriyama, MD Hiroko Ochiai, MD, PhD Yoshikazu Inoue, MD, PhD Yoshiaki Sakamoto, MD, PhD Naoki Yamamoto, CMDT, PhD Toshiaki Utsumi, MD, PhD Kazuo Kishi, MD, PhD Takayuki Okumoto, MD, PhD Akihiro Matsuura, MD, PhD Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture Plastic and Reconstructive Surgery, Global Open |
| author_facet |
Erika Kuriyama, MD Hiroko Ochiai, MD, PhD Yoshikazu Inoue, MD, PhD Yoshiaki Sakamoto, MD, PhD Naoki Yamamoto, CMDT, PhD Toshiaki Utsumi, MD, PhD Kazuo Kishi, MD, PhD Takayuki Okumoto, MD, PhD Akihiro Matsuura, MD, PhD |
| author_sort |
Erika Kuriyama, MD |
| title |
Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture |
| title_short |
Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture |
| title_full |
Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture |
| title_fullStr |
Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture |
| title_full_unstemmed |
Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with Contracture |
| title_sort |
characterization of the capsule surrounding smooth and textured tissue expanders and correlation with contracture |
| publisher |
Wolters Kluwer |
| series |
Plastic and Reconstructive Surgery, Global Open |
| issn |
2169-7574 |
| publishDate |
2017-07-01 |
| description |
Background:. Capsular contracture is a common complication after breast augmentation surgery. This study pathologically evaluated the soft-tissue response to surface modifications in both smooth and textured tissue expander prostheses.
Methods:. Smooth tissue expanders and textured tissue expanders in 5 cases each were used for breast reconstruction after mastectomy. Histological samples were harvested from the capsules when the tissue expanders were replaced by silicone implants. Collagen orientation and cellular responses were assessed histologically. Capsular contracture was evaluated using the Baker classification 6 months and 2 years after the removal of the tissue expander.
Results:. The capsules surrounding the smooth tissue expanders tended to produce more contracture than those surrounding the textured tissue expanders. The collagen architecture of the capsules of the smooth tissue expanders showed random orientation with fragmentation. Conversely, the capsules of the textured tissue expanders showed parallel orientation with collagen bundles of almost normal structure. Significantly more fibrils of elastin and myofibroblasts were found in the capsules surrounding the smooth tissue than in those surrounding the textured ones.
Conclusions:. The collagen fibers surrounding the smooth tissue expanders could be cracked during expansion, which may lead to scarring and contracture. Conversely, the collagen orientation surrounding the textured tissue expanders was excellent. Moreover, the increase in elastic fibers and myofibroblasts in the capsules surrounding the smooth tissue expanders may be associated with in vivo contraction patterns. Therefore, the surface type of tissue expanders affects capsular contraction after replacement with definitive implants. |
| url |
http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001403 |
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doaj-6b82ccef787d4000aa78abf00b051fce2020-11-24T21:15:28ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742017-07-015710.1097/GOX.0000000000001403gox-5-e1403Characterization of the Capsule Surrounding Smooth and Textured Tissue Expanders and Correlation with ContractureErika Kuriyama, MD0Hiroko Ochiai, MD, PhD1Yoshikazu Inoue, MD, PhD2Yoshiaki Sakamoto, MD, PhD3Naoki Yamamoto, CMDT, PhD4Toshiaki Utsumi, MD, PhD5Kazuo Kishi, MD, PhD6Takayuki Okumoto, MD, PhD7Akihiro Matsuura, MD, PhD8From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.From the *Department of Plastic and Reconstructive Surgery, Fujita Health University, Aichi, Japan; †Department of Plastic and Reconstructive Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; ‡Department of Plastic and Reconstructive Surgery, Keio University Hospital, Tokyo, Japan; §Laboratory of Molecular Biology, Institute of Joint Research, Fujita Health University, Aichi, Japan; ¶Department of Breast Surgery, Fujita Health University, Aichi, Japan; and ‖Department of Molecular Pathology, Fujita Health University Graduate School of Medicine, Aichi, Japan.Background:. Capsular contracture is a common complication after breast augmentation surgery. This study pathologically evaluated the soft-tissue response to surface modifications in both smooth and textured tissue expander prostheses. Methods:. Smooth tissue expanders and textured tissue expanders in 5 cases each were used for breast reconstruction after mastectomy. Histological samples were harvested from the capsules when the tissue expanders were replaced by silicone implants. Collagen orientation and cellular responses were assessed histologically. Capsular contracture was evaluated using the Baker classification 6 months and 2 years after the removal of the tissue expander. Results:. The capsules surrounding the smooth tissue expanders tended to produce more contracture than those surrounding the textured tissue expanders. The collagen architecture of the capsules of the smooth tissue expanders showed random orientation with fragmentation. Conversely, the capsules of the textured tissue expanders showed parallel orientation with collagen bundles of almost normal structure. Significantly more fibrils of elastin and myofibroblasts were found in the capsules surrounding the smooth tissue than in those surrounding the textured ones. Conclusions:. The collagen fibers surrounding the smooth tissue expanders could be cracked during expansion, which may lead to scarring and contracture. Conversely, the collagen orientation surrounding the textured tissue expanders was excellent. Moreover, the increase in elastic fibers and myofibroblasts in the capsules surrounding the smooth tissue expanders may be associated with in vivo contraction patterns. Therefore, the surface type of tissue expanders affects capsular contraction after replacement with definitive implants.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001403 |