Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
MicroRNA-29b (miR-29b) expression has been shown to be reduced in non-small–cell lung cancer (NSCLC) tissues. Here, we have identified the oncogene cyclin-dependent protein kinase 6 (CDK6) as a direct target of miR-29b in lung cancer. We hypothesized that in vivo restoration of miR-29b and thus targ...
Main Authors: | Yun Wu, Melissa Crawford, Yicheng Mao, Robert J Lee, Ian C Davis, Terry S Elton, L James Lee, Serge P Nana-Sinkam |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-01-01
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Series: | Molecular Therapy: Nucleic Acids |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253116301457 |
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