Variable Expression of Programmed Cell Death Protein 1-Ligand 1 in Kidneys Independent of Immune Checkpoint Inhibition

Variable Expression of Programmed Cell Death Protein 1-Ligand 1 in Kidneys Independent of Immune Checkpoint Inhibition

ContextDue to recent advantages in cancer therapy, immune checkpoint inhibitors (ICIs) are new classes of drugs targeting programmed cell death protein 1 (PD-1) or its ligand programmed cell death protein 1-ligand 1 (PD-L1) used in many cancer therapies. Acute interstitial nephritis (AIN) is a poten...

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Bibliographic Details
Main Authors: Samy Hakroush, Sarah Birgit Kopp, Désirée Tampe, Ann-Kathrin Gersmann, Peter Korsten, Michael Zeisberg, Björn Tampe
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
programmed cell death protein 1-ligand 1 (PD-L1)
checkpoint inhibition
immune-related adverse events (irAE)
acute kidney injury
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.624547/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.624547/full

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