Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.
The mechanistic target of rapamycin (MTOR) pathway regulates cell growth, energy homeostasis, apoptosis, and immune response. The regulatory associated protein of MTOR encoded by the RPTOR gene is a key component of this pathway. A previous survey of candidate genes found that RPTOR contains multipl...
Main Authors: | Chang Sun, Catherine Southard, David B Witonsky, Ralf Kittler, Anna Di Rienzo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-10-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2965758?pdf=render |
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