Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae, France

Carbapenem Resistance Conferred by OXA-48 in K2-ST86 Hypervirulent Klebsiella pneumoniae, France

We recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality. Convergence of hypervirulent K. pneumoniae toward resistance could...

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Bibliographic Details
Main Authors: Racha Beyrouthy, Guillaume Dalmasso, Aurélien Birer, Frédéric Robin, Richard Bonnet
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2020-07-01
Series:Emerging Infectious Diseases
Subjects:
β-lactamase
OXA-48
hypervirulent Klebsiella pneumoniae
next-generation sequencing
France
antimicrobial resistance
Online Access:https://wwwnc.cdc.gov/eid/article/26/7/19-1490_article
Description
Summary:We recovered 2 carbapenem-resistant K2-ST86 hypermucoviscous Klebsiella pneumoniae isolates from patients in France. The isolates had genetic attributes of hypervirulent K. pneumoniae but differed in ability to cause mouse lethality. Convergence of hypervirulent K. pneumoniae toward resistance could cause a health crisis because such strains could be responsible for severe and untreatable infections.
ISSN:1080-6040
1080-6059

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