Apatinib Mesylate Inhibits the Proliferation and Metastasis of Epithelioid Malignant Peritoneal Mesothelioma In Vitro and In Vivo

Apatinib Mesylate Inhibits the Proliferation and Metastasis of Epithelioid Malignant Peritoneal Mesothelioma In Vitro and In Vivo

ObjectiveMalignant peritoneal mesothelioma (MPM) is a rare malignancy with few effective molecular therapies. In this study, we evaluated the anti-tumor activity and safety of apatinib, a vascular endothelial growth factor receptor 2 inhibitor, in MPM in vitro and in vivo.MethodsWe established sever...

Full description

Bibliographic Details
Main Authors: Zhi-Ran Yang, Zhi-Gao Chen, Xue-Mei Du, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
malignant peritoneal mesothelioma
patient-derived xenograft model
primary cell line
toxicity
apatinib
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.585079/full

Similar Items

Similar Items