The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides.

The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides.

The well-recognized phospholipids (PLs) of Mycobacterium tuberculosis (Mtb) include several acidic species such as phosphatidylglycerol (PG), cardiolipin, phosphatidylinositol and its mannoside derivatives, in addition to a single basic species, phosphatidylethanolamine. Here we demonstrate that an...

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Bibliographic Details
Main Authors: Erin Maloney, Dorota Stankowska, Jian Zhang, Marek Fol, Qi-Jian Cheng, Shichun Lun, William R Bishai, Malini Rajagopalan, Delphi Chatterjee, Murty V Madiraju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2713425?pdf=render

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