If Channel Inhibition - Ivabradine for the Treatment of Heart Failure

The novel first-in-class If channel antagonist, Ivabradine, is effective in improving clinical outcomes and functional capacity, in patients with HF, as well as demonstrating useful anti-anginal and protective anti-ischaemic effects. It can help improve heart rate control and can be usefully co-admi...

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Main Authors: Giuseppe MC Rosano, Cristiana Vitale
Format: Article
Language:English
Published: Barcaray International 2019-01-01
Series:International Cardiovascular Forum Journal
Subjects:
Online Access:https://icfjournal.org/index.php/icfj/article/view/599/pdf
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spelling doaj-6be4d0f4f271424c8a50e2f1d042b26e2020-11-25T03:26:20ZengBarcaray InternationalInternational Cardiovascular Forum Journal2410-26362409-34242019-01-01172628https://doi.org/10.17987/icfj.v17i0.599If Channel Inhibition - Ivabradine for the Treatment of Heart FailureGiuseppe MC Rosano0Cristiana Vitale1Centre for Clinical & Basic Research IRCCS San Raffaele Pisana, via della Pisana, 235, 00163 Rome, ItalyDepartment of Medical Sciences, IRCCS San Raffaele Pisana, Rome, ItalyThe novel first-in-class If channel antagonist, Ivabradine, is effective in improving clinical outcomes and functional capacity, in patients with HF, as well as demonstrating useful anti-anginal and protective anti-ischaemic effects. It can help improve heart rate control and can be usefully co-administered with beta blockers on HFrEF patients with residually elevated resting sinus rhythm heart rate. We review the clinical trial evidence for the benefits of Ivabradine in the treatment of heart failure.https://icfjournal.org/index.php/icfj/article/view/599/pdfheart failureivabradineclinical trial
collection DOAJ
language English
format Article
sources DOAJ
author Giuseppe MC Rosano
Cristiana Vitale
spellingShingle Giuseppe MC Rosano
Cristiana Vitale
If Channel Inhibition - Ivabradine for the Treatment of Heart Failure
International Cardiovascular Forum Journal
heart failure
ivabradine
clinical trial
author_facet Giuseppe MC Rosano
Cristiana Vitale
author_sort Giuseppe MC Rosano
title If Channel Inhibition - Ivabradine for the Treatment of Heart Failure
title_short If Channel Inhibition - Ivabradine for the Treatment of Heart Failure
title_full If Channel Inhibition - Ivabradine for the Treatment of Heart Failure
title_fullStr If Channel Inhibition - Ivabradine for the Treatment of Heart Failure
title_full_unstemmed If Channel Inhibition - Ivabradine for the Treatment of Heart Failure
title_sort if channel inhibition - ivabradine for the treatment of heart failure
publisher Barcaray International
series International Cardiovascular Forum Journal
issn 2410-2636
2409-3424
publishDate 2019-01-01
description The novel first-in-class If channel antagonist, Ivabradine, is effective in improving clinical outcomes and functional capacity, in patients with HF, as well as demonstrating useful anti-anginal and protective anti-ischaemic effects. It can help improve heart rate control and can be usefully co-administered with beta blockers on HFrEF patients with residually elevated resting sinus rhythm heart rate. We review the clinical trial evidence for the benefits of Ivabradine in the treatment of heart failure.
topic heart failure
ivabradine
clinical trial
url https://icfjournal.org/index.php/icfj/article/view/599/pdf
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