Serological tools for detection of Trichinella infection in animals and humans

• Main Authors: Yong Yang, Ya Nan Cai, Ming Wei Tong, Na Sun, Yin Hua Xuan, Yan Jun Kang, Isabelle Vallée, Pascal Boireau, Shi peng Cheng, Ming Yuan Liu
• Format: Article
• Language: English
• Published: Elsevier 2016-12-01
• Series: One Health
• Subjects: Trichinellosis; Trichinella; Serological tools; Man; Animal
• Online Access: http://www.sciencedirect.com/science/article/pii/S2352771416000021

Trichinellosis is a serious foodborne zoonotic disease. It is an important threat to public health in both developing and developed countries. Human infections are strongly associated with consuming undercooked meat containing infective Trichinella larvae. The development of serological tools has enabled seroepidemiological studies and contributed to our knowledge on the importance of this parasite. Serological tests can also help the diagnosis of parasite infections in humans and the surveillance of animals. Generally speaking, serological techniques include detection methods for specific antibodies and for circulating parasite antigens in the serum or tissue fluids. Here, we present a comprehensive review of various methods used in the detection of antibodies against Trichinella and circulating parasite antigens in animals and humans.