Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential
Abstract Background The impacts of man-made chemicals, in particular of persistent organic pollutants, are multifactorial as they may affect the integrity of ecosystems, alter biodiversity and have undesirable effects on many organisms. We have previously demonstrated that the belowground mycobiota...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
|
Series: | Microbiome |
Online Access: | http://link.springer.com/article/10.1186/s40168-018-0589-y |
id |
doaj-6c0623d605ed4e90a044840223076c12 |
---|---|
record_format |
Article |
spelling |
doaj-6c0623d605ed4e90a044840223076c122020-11-25T01:33:28ZengBMCMicrobiome2049-26182018-11-016111310.1186/s40168-018-0589-ySpecialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potentialCelso Martins0Adélia Varela1Céline C. Leclercq2Oscar Núñez3Tomáš Větrovský4Jenny Renaut5Petr Baldrian6Cristina Silva Pereira7Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB NOVA)Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB NOVA)Integrative biology platform, Environmental Research and Technology Platform, Luxembourg Institute of Science and TechnologyDepartment of Chemical Engineering and Analytical Chemistry, University of BarcelonaLaboratory of Environmental Microbiology, Institute of Microbiology of the Czech Academy of SciencesIntegrative biology platform, Environmental Research and Technology Platform, Luxembourg Institute of Science and TechnologyLaboratory of Environmental Microbiology, Institute of Microbiology of the Czech Academy of SciencesInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB NOVA)Abstract Background The impacts of man-made chemicals, in particular of persistent organic pollutants, are multifactorial as they may affect the integrity of ecosystems, alter biodiversity and have undesirable effects on many organisms. We have previously demonstrated that the belowground mycobiota of forest soils acts as a buffer against the biocide pollutant pentachlorophenol. However, the trade-offs made by mycobiota to mitigate this pollutant remain cryptic. Results Herein, we demonstrate using a culture-dependent approach that exposure to pentachlorophenol led to alterations in the composition and functioning of the metacommunity, many of which were not fully alleviated when most of the biocide was degraded. Proteomic and physiological analyses showed that the carbon and nitrogen metabolisms were particularly affected. This dysregulation is possibly linked to the higher pathogenic potential of the metacommunity following exposure to the biocide, supported by the secretion of proteins related to pathogenicity and reduced susceptibility to a fungicide. Our findings provide additional evidence for the silent risks of environmental pollution, particularly as it may favour the development of pathogenic trade-offs in fungi, which may impose serious threats to animals and plant hosts.http://link.springer.com/article/10.1186/s40168-018-0589-y |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Celso Martins Adélia Varela Céline C. Leclercq Oscar Núñez Tomáš Větrovský Jenny Renaut Petr Baldrian Cristina Silva Pereira |
spellingShingle |
Celso Martins Adélia Varela Céline C. Leclercq Oscar Núñez Tomáš Větrovský Jenny Renaut Petr Baldrian Cristina Silva Pereira Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential Microbiome |
author_facet |
Celso Martins Adélia Varela Céline C. Leclercq Oscar Núñez Tomáš Větrovský Jenny Renaut Petr Baldrian Cristina Silva Pereira |
author_sort |
Celso Martins |
title |
Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential |
title_short |
Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential |
title_full |
Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential |
title_fullStr |
Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential |
title_full_unstemmed |
Specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential |
title_sort |
specialisation events of fungal metacommunities exposed to a persistent organic pollutant are suggestive of augmented pathogenic potential |
publisher |
BMC |
series |
Microbiome |
issn |
2049-2618 |
publishDate |
2018-11-01 |
description |
Abstract Background The impacts of man-made chemicals, in particular of persistent organic pollutants, are multifactorial as they may affect the integrity of ecosystems, alter biodiversity and have undesirable effects on many organisms. We have previously demonstrated that the belowground mycobiota of forest soils acts as a buffer against the biocide pollutant pentachlorophenol. However, the trade-offs made by mycobiota to mitigate this pollutant remain cryptic. Results Herein, we demonstrate using a culture-dependent approach that exposure to pentachlorophenol led to alterations in the composition and functioning of the metacommunity, many of which were not fully alleviated when most of the biocide was degraded. Proteomic and physiological analyses showed that the carbon and nitrogen metabolisms were particularly affected. This dysregulation is possibly linked to the higher pathogenic potential of the metacommunity following exposure to the biocide, supported by the secretion of proteins related to pathogenicity and reduced susceptibility to a fungicide. Our findings provide additional evidence for the silent risks of environmental pollution, particularly as it may favour the development of pathogenic trade-offs in fungi, which may impose serious threats to animals and plant hosts. |
url |
http://link.springer.com/article/10.1186/s40168-018-0589-y |
work_keys_str_mv |
AT celsomartins specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT adeliavarela specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT celinecleclercq specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT oscarnunez specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT tomasvetrovsky specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT jennyrenaut specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT petrbaldrian specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential AT cristinasilvapereira specialisationeventsoffungalmetacommunitiesexposedtoapersistentorganicpollutantaresuggestiveofaugmentedpathogenicpotential |
_version_ |
1725077031784284160 |