Anthracenedione Derivatives as Anticancer Agents Isolated from Secondary Metabolites of the Mangrove Endophytic Fungi

Anthracenedione Derivatives as Anticancer Agents Isolated from Secondary Metabolites of the Mangrove Endophytic Fungi

In this article, we report anticancer activity of 14 anthracenedione derivatives separated from the secondary metabolites of the mangrove endophytic fungi Halorosellinia sp. (No. 1403) and Guignardia sp. (No. 4382). Some of them inhibited potently the growth of KB and KBv200 cells, among which compo...

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Bibliographic Details
Main Authors: Jian-ye Zhang, Li-yang Tao, Yong-ju Liang, Li-ming Chen, Yan-jun Mi, Li-sheng Zheng, Fang Wang, Zhi-gang She, Yong-cheng Lin, Kenneth Kin Wah To, Li-wu Fu
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Marine Drugs
Subjects:
mangrove endophytic fungi
anthracenedione derivatives
anticancer
apoptosis
structure-activity relationship
Online Access:http://www.mdpi.com/1660-3397/8/4/1469/

Internet

http://www.mdpi.com/1660-3397/8/4/1469/

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