<it>LRRK2</it> knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors
<p>Abstract</p> <p>Mutations in the <it>LRRK2</it> gene are the most common cause of genetic Parkinson’s disease. Although the mechanisms behind the pathogenic effects of <it>LRRK2</it> mutations are still not clear, data emerging from <it>in vitro<...
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-05-01
|
Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://www.molecularneurodegeneration.com/content/7/1/25 |