Geniposide protection against Aβ1-42 toxicity correlates with mTOR inhibition and enhancement of autophagy

Overactivation of the PI3-K/Akt/mTOR signaling pathway and inhibition of autophagy in the brain are involved in Alzheimer’s disease. The present paper’s goal was to explore the potential mechanisms of geniposide to protect against Alzheimer’s disease. We treated the human neuroblastoma SH-SY5Y c...

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Bibliographic Details
Main Authors: Dong-Xing Liu, Di Zhang, Wei-Min Hu, Yan-Fang Chang, Xiao-Hui Wang, Lin Li
Format: Article
Language:English
Published: IMR (Innovative Medical Research) Press Limited 2021-03-01
Series:Journal of Integrative Neuroscience
Subjects:
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Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1616655613722-1850893816.pdf