High-resolution visualization of H3 variants during replication reveals their controlled recycling
Epigenetic modifications are a key contributor to cell identity, and their propagation is crucial for proper development. Here the authors use a super-resolution microscopy approach to reveal how histone variants are faithfully transmitted during genome duplication, and reveal an important role for...
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2018-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05697-1 |
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doaj-6c76f62ba9cb4bb9903ec28038c670812021-05-11T10:29:34ZengNature Publishing GroupNature Communications2041-17232018-08-019111710.1038/s41467-018-05697-1High-resolution visualization of H3 variants during replication reveals their controlled recyclingCamille Clément0Guillermo A. Orsi1Alberto Gatto2Ekaterina Boyarchuk3Audrey Forest4Bassam Hajj5Judith Miné-Hattab6Mickaël Garnier7Zachary A. Gurard-Levin8Jean-Pierre Quivy9Geneviève Almouzni10Institut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR168, Laboratoire Physico-ChimieSorbonne Universités, UPMC Univ Paris 06, CNRS, UMR3664Sorbonne Universités, UPMC Univ Paris 06, CNRS, UMR3664Institut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerInstitut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le CancerEpigenetic modifications are a key contributor to cell identity, and their propagation is crucial for proper development. Here the authors use a super-resolution microscopy approach to reveal how histone variants are faithfully transmitted during genome duplication, and reveal an important role for the histone chaperone ASF1 in the redistribution of parental histones.https://doi.org/10.1038/s41467-018-05697-1 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Camille Clément Guillermo A. Orsi Alberto Gatto Ekaterina Boyarchuk Audrey Forest Bassam Hajj Judith Miné-Hattab Mickaël Garnier Zachary A. Gurard-Levin Jean-Pierre Quivy Geneviève Almouzni |
spellingShingle |
Camille Clément Guillermo A. Orsi Alberto Gatto Ekaterina Boyarchuk Audrey Forest Bassam Hajj Judith Miné-Hattab Mickaël Garnier Zachary A. Gurard-Levin Jean-Pierre Quivy Geneviève Almouzni High-resolution visualization of H3 variants during replication reveals their controlled recycling Nature Communications |
author_facet |
Camille Clément Guillermo A. Orsi Alberto Gatto Ekaterina Boyarchuk Audrey Forest Bassam Hajj Judith Miné-Hattab Mickaël Garnier Zachary A. Gurard-Levin Jean-Pierre Quivy Geneviève Almouzni |
author_sort |
Camille Clément |
title |
High-resolution visualization of H3 variants during replication reveals their controlled recycling |
title_short |
High-resolution visualization of H3 variants during replication reveals their controlled recycling |
title_full |
High-resolution visualization of H3 variants during replication reveals their controlled recycling |
title_fullStr |
High-resolution visualization of H3 variants during replication reveals their controlled recycling |
title_full_unstemmed |
High-resolution visualization of H3 variants during replication reveals their controlled recycling |
title_sort |
high-resolution visualization of h3 variants during replication reveals their controlled recycling |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2018-08-01 |
description |
Epigenetic modifications are a key contributor to cell identity, and their propagation is crucial for proper development. Here the authors use a super-resolution microscopy approach to reveal how histone variants are faithfully transmitted during genome duplication, and reveal an important role for the histone chaperone ASF1 in the redistribution of parental histones. |
url |
https://doi.org/10.1038/s41467-018-05697-1 |
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