Lactonase Specificity Is Key to Quorum Quenching in Pseudomonas aeruginosa

Lactonase Specificity Is Key to Quorum Quenching in Pseudomonas aeruginosa

The human opportunistic pathogen Pseudomonas aeruginosa orchestrates the expression of many genes in a cell density-dependent manner by using quorum sensing (QS). Two acyl-homoserine lactones (AHLs) are involved in QS circuits and contribute to the regulation of virulence factors production, biofilm...

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Bibliographic Details
Main Authors: Benjamin Rémy, Laure Plener, Philippe Decloquement, Nicholas Armstrong, Mikael Elias, David Daudé, Éric Chabrière
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
quorum sensing
Pseudomonas aeruginosa
quorum quenching
acyl-homoserine lactones
lactonases
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00762/full

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