TRPV1 and TRPV1-Expressing Nociceptors Mediate Orofacial Pain Behaviors in a Mouse Model of Orthodontic Tooth Movement

Orthodontic force produces mechanical irritation and inflammation in the periodontium, which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic pain is ineffective. Elucidating underlying neural mechanisms is critical to improving the management of orthodontic pain....

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Bibliographic Details
Main Authors: Sheng Wang, Martin Kim, Zayd Ali, Katherine Ong, Eung-Kwon Pae, Man-Kyo Chung
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01207/full